For Gideon, Infection With a Common Virus Caused Rare Birth Defects
When Kathleen Muldoon had her second child everything was going smoothly. The delivery was short, the babys APGAR score was good and he was a healthy weight. Everyone said he was amazing, says Muldoon.
But when a doctor noticed that Gideon was jaundiced, everything changed. Nurses put him under a fluorescent light to treat the problem. But it didnt work. Instead, he developed a red rash all over his body.
Blood work indicated newborn Gideon was infected with a virus Muldoon had never heard of: Cytomegalovirus or CMV – a virus that can cause severe birth defects.
Muldoon, 40 of Peoria, Ariz. , remembers the pediatrician coming in to deliver the bad news. He couldnt even make eye contact, she says.
Gideon was diagnosed with extensive brain damage, spastic quadriplegic cerebral palsy, visual impairment, epilepsy and microcephaly – thats the neurological condition also caused by the Zika virus, where the babys head is abnormally small.
Gideon spent the first four weeks of his life in the neonatal intensive care unit. Gideons case is unusually severe. Every year about 40,000 babies are born in the U.S. infected with CMV. Most wont have any symptoms.
But one in five will have CMV-related problems, like hearing loss, cognitive delay or neurological problems like Gideon. Cytomegalovirus Is Everywhere.
Like cold and flu viruses, CMV is transmitted from person to person. It travels in bodily fluids like blood, urine and saliva. It is extremely common, according to Dr. Joseph Bocchini, a pediatric infectious disease specialist with Louisiana State University.
Cytomegalovirus is everywhere, he says. It is hard to avoid. By middle age, more than half of adults are infected. By age 5, nearly 1 in 3 children have it.
They pick it up from kissing or touching someone or something, like a door handle, table or toy thats been contaminated. The virus can live on these objects for hours.
Once youve been infected with CMV, the virus stays with you for life.
For most people, CMV isnt a problem. It rarely causes symptoms and if it does theyre pretty mild, similar to a cold, says Dr.Brenna Hughes, an associate professor of obstetrics and gynecology at Duke University School of Medicine.
CMV usually just causes sniffles and possibly a low grade fever, she says.
However, CMV infection can cause serious health problems for people with weakened immune systems, such as individuals with HIV or those who have an organ transplant. And it can be a big problem for pregnant women.
Timing Can Make All The Difference.
CMV can pass through the placenta to the fetus, but that doesnt happen very often. If a woman was infected with CMV before getting pregnant, theres a less than 1 percent chance shell pass the infection on to her fetus.
And even if the baby is infected with CMV, the majority dont have any symptoms. But timing can make all the difference, says Hughes.
If a woman gets infected for the very first time when shes pregnant, the virus is more dangerous probably because theres more virus and less of an immune response already present in the mother, says infectious disease specialist Bocchini.
About 10 percent of these babies will likely have CMV-related problems and about 3 percent of them will be severely affected like Gideon.
The stage of pregnancy when first infected also makes a difference. If the mothers in her first trimester, when organs like the brain are developing, the consequences can be devastating. Doctors told Muldoon she was likely infected during her first trimester.
Today, Gideon is 3 years old. He uses a wheelchair, cant see well or speak, but he loves sounds and music.
He giggles loudly when he hears his mother sing. But Muldoon is worried that even his precious hearing may be in jeopardy.
CMV can cause hearing loss three to five years after the initial infection, and Gideon is starting to show some hearing loss in his left ear. I Had Never Heard Of This Virus.
When Muldoon reflects on her pregnancy, she is astonished that she didnt know anything about CMV before she had Gideon, especially since shes an anthropologist who teaches anatomy to medical students at Arizonas Midwestern University.
And yet I had never heard of this virus, she says. Muldoons not alone.
A survey from the National CMV Foundation found only 9 percent of women knew about the virus and a study by the Centers for Disease Control and Prevention found fewer than half of OB-GYNs discuss CMV with their patients.
Hughes, who is also a spokesperson for the American College of Obstetricians and Gynecologists (ACOG,) says pregnant women are generally told the best way to avoid infection is careful hand washing, and to avoid interacting with sick people.
Until 2015 ACOG recommended more aggressive prevention efforts, especially for women who are around toddlers, who can be hot zones for viral transmission with all their dribbling and drooling.
They recommended pregnant women wash their hands every single time after they handle a childs toy or laundry and not to kiss a child on the face where contaminated saliva might be present.
These suggestions were scrapped when no conclusive evidence was found that they actually prevent infection, says Hughes.
Theres currently a debate in the medical community about whether to screen all newborns for CMV. Many doctors are skeptical, since there is no proven treatment.
One study suggests antiviral medication in the first six months of life might decrease the risk of later hearing loss and cognitive decline.
This is a challenging virus, says Dr. Mobeen Rathore, an infectious disease specialist with the University of Florida. We need better diagnostic tools, better treatments and better ways to manage infection, he says.
Obstetrician Hughes agrees, and says further research and larger studies are needed.
She notes that Congress approved $1 billion to support Zika virus research and prevention, but CMV does not have a line item for funding in the annual budget — this, despite the fact that CMV is far more common in the U.S.
than Zika.
For more infomation >> Jewelry store apologizes for billboard - Duration: 0:46. 
For more infomation >> Glycine for Better Sleep - Fitbits Australia - Duration: 3:52. 
For more infomation >> Baby Learn Colors with My Talking Tom Colours for Animation Education Cartoon Video Android - Duration: 7:58. 
For more infomation >> How to Crochet A Baby Blanket: For Beginners - Duration: 15:28. 
Không có nhận xét nào:
Đăng nhận xét