Thứ Ba, 30 tháng 1, 2018

Waching daily Jan 31 2018

Hi! I would like to give you a brief introduction into what we do in the laboratory.

We are absolutely fascinated with the brain and the complexity of the brain, with its eighty billion neurons and its intricate connectivity.

We are trying to study the brain at several different levels

ranging from the study of single neurons and its input/output properties to the study of

circuits, where several neurons are aggregated into recurrent motives.

Secondly, we are interested in mechanisms of CNS disorders, and we are absolutely

convinced that CNS disorders can only be understood at the circuit level

So we are applying all these techniques the study of epilepsy, one of the most common CNS disorders.

We've assembled a great team

to address these questions at all these levels, so I would like to take you on a tour through the lab.

My area of interest is in

investigating how neurons

transform synaptic input into an appropriate

output and more specifically into how their dendrites, their side of input actually act as

Computational units. To tackle these questions, we use some sophisticated

electrophysiological and imaging techniques that employ two-photon pulsed lasers.

We firstly patch onto cells, fill the cells with a fluorescent Dye, and then we can actually stimulate

individual synapses using two photon uncaging of glutamate.

In our lab, we're interested in how the Hippocampus computes information.

Therefore, we investigate networks

And network patterns in vivo. To do so, we perform two photon calcium imaging in neuronal samples

This allows us to gain deeper insights how different states of brain activity are correlated to behavior

Having all these different techniques in mind which we perform here in the lab, one can think of an implementation in medical research.

Epilepsy is a severe disorder

which finally causes seizures in patients. It is our interest to

Investigate these seizures on a network level and for this purpose, we are using

electrophysiological and pharmacological approaches

We can investigate

how different antiepileptic drugs act on a network level in the brain and we want to know

why different antiepileptic drugs work in some patients and why some patients do show a pharmacoresistance.

You

For more infomation >> This is what we do | Life & Brain: The Beck Group - Duration: 3:26.

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This Holy Trinity Is Mother Of All Cures - Duration: 2:29.

This Holy Trinity Is Mother Of All Cures,Garlic, Apple Cider Vinegar And Honey: Natural Combination

That Treats Many Diseases!

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On the other hand, garlic contains plenty of allicin, which is an anti-inflammatory

compound that fights cancer and slows down the aging process.

Finally, apple cider vinegar is beyond healthy for many diseases and preventing them in the

first place.

A few of the issues that ACV treat are diabetes, obesity, and indigestion.

Now, imagine combining these three together?!

Well, if that is not one powerful remedy, we do not know what it is.

One study confirmed the benefits of this remedy for cancer-related diseases.

As it was confirmed, cancer patients who have used it regularly, showed significant health

improvements and diminished cancer symptoms.

Other than this, the treatment has been successful in dealing with high cholesterol and high

blood pressure levels.

It is best to take this solution in the mornings, before consuming any food or liquids.

Ingredients:

1 cup apple cider vinegar 1 cup honey, raw and organic

10 garlic cloves Preparation:

Mix all ingredients until content evens out.

Pour mix in a container and cool it.

The remedy has finest effects for 5 days, so make the most of it.

Taking it after 5 days have gone by will not harm you, but the benefits are not the same.

Good to know

To get best results, take 2 tablespoons of the treatment every morning before your meal.

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For more infomation >> This Holy Trinity Is Mother Of All Cures - Duration: 2:29.

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What is lower pole constricted breast?-Dr.Hourglass - Duration: 6:44.

Hi, this is Dr. Hourglass, and welcome to another video in our channel Wonder Breasts.

Today we are going to discuss: What is a lower pole constricted breast?

In this channel we discuss everything related to breast surgery.

Welcome back!

The shape, size, and balance of the breasts play a crucial role in outlining the physical beauty of a woman,

apart from setting her self-esteem and sense of femininity.

A woman with normal and aesthetically appealing breasts feels more confident and enjoys

a good quality of life than a woman with poorly shaped breasts.

Constriction of the breasts is a pathologic condition that affects many women.

It starts at puberty, and the condition features constriction of the ring at the base of the breast

and lack of tissue in the breasts.

The lower pole constricted breasts show tightening along the lower pole of the breasts,

causing the breasts to appear abnormal and in the shape of a tube.

This condition often happens as a result of herniation of the breast tissue into the nipple-areolar complex.

This causes the breasts to look bulging or swollen and abnormal in shape.

In a lower pole constricted breast, the base of the breast is almost absent, underdeveloped,

or defective both vertically and horizontally.

This is often coupled by a hypoplastic breast tissue or an inframammary create that is higher, or both.

There are other aesthetic problems that may follow the lower pole constricted breasts.

These include asymmetrical, saggy, and poorly balanced breasts.

As to what factors exactly cause lower pole constricted breasts is not yet known.

Studies indicate the condition might be caused by multiple factors, including genetic tendencies.

Treatment for lower pole constricted breasts can be custom-tailored to your unique needs and requirements.

Each patient has a varying degree and type of constriction in the lower pole of the breasts.

The common treatment options include breast implant surgery and tissue expansion.

The use of breast lift might also become inevitable to treat the condition.

Even though a combination of these treatments is used to treat lower pole constricted breasts effectively,

constriction of new breast tissue by sinking your skin incision and soft tissue expansion

also delivers reliable and effective outcomes.

Typically, the implant is placed over the muscle to expand the soft tissue envelope more efficiently.

If you have lower pole constricted breasts, you should consult with a board-certified plastic surgeon

to explore the treatment options and determine your candidacy for the surgery.

In this video, we discussed: What is a lower pole constricted breast?

Next week we will discuss: Gummy bears: What are these new implants?

Remember to comment below, share this video, like this video, and subscribe to our channel

for more information, here at the Wonder Breasts channel, only on YouTube.

Also, you can log on to our website,

for more information about your procedure and to see amazing surgical results.

For more infomation >> What is lower pole constricted breast?-Dr.Hourglass - Duration: 6:44.

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Right Angle: And The Winner Is.... Digital Actors! - Duration: 13:05.

Well what we in Los Angeles call kudos season has just gotten into top gear

with the announcement of the Academy Award nominees and I think it's probably

in the interest of all of us to take a look at one of these categories and see

what the world's political situation looks like. Hi everybody I'm Bill Whittle

here with Steve Green and Scott Ott and this is about your post-Oscars Oscars. So

here's what I think are the five best performances of 2017 and the nominees

for best male actor are:

"Alright, team Osiris the light is green."

"Brooks isn't a corporal anymore. Your sergeant now.

You're the commander of the Marines on this ship.

My honor, sir.

"We should contact Admiral Raines now, commander."

"No. Staff Sergeant Omar said to pick your mission,

don't let it pick you. That's exactly what we're gonna do."

Ho ho, ha ha, did you see what I did there? There's a reason for this. Certainly

those of us who are conservatives, the half of the country that's routinely

insulted by all of the glitterati and all of the rest of the highfalutin

limousine liberals who talk about open borders from behind their private

security fenced in compounds and all the rest of this hypocrisy - all of this is on

its way out. The Oscars used to be something that was just a cultural event,

now it's just kind of like a, you know Thursday night football game,

essentially it's going to essentially disappear. One of the reasons is that

entertainment is moving away from feature films and TV into things like

content produced by users on YouTube, some of these getting billions of views.

There's not a TV show in the world that ever got billions of views and also

so much of the focus of the creative arts today is going into computer games.

So as you can see from the examples I picked, we're not there yet but we are

getting perilously close to this idea of digital actors and so on and this is

what I'd like to discuss today: the digital future of entertainment. Steve,

let's start with you. I suspect that it will be available - it's already available

to Hollywood - to produce characters that are essentially indistinguishable from

digital characters, essentially indistinguishable from real people.

Certainly within the next two or three years on the high level it'll be routine.

This technology moves downhill very very quickly. What do you think that says when

a screenwriter is not only able to write a character but perhaps in

conjunction with the director is able to design the character - is to create

the actor that they think is perfect for this. Does that worry you at all or do

you think there's some interesting ground to be made there? No it doesn't

worry me in the slightest and let me tell you why. How many stories have been

written, by writers of course, about how Hollywood screwed up their book? )r about

how the singer screwed up their song? I've got Ray Charles in The Count Basie

Orchestra doing an old number called "Mom, Look What They Did to My Song." So

this is the age-old lament. That somewhere between the writer and the

audience, you've got a money-grubbing producer, you've got an egotistical

director, you have idiot actors who all kind of conspire to ruin the writer's

vision and I remember during the the big writers strike of maybe this is 20 years

ago now, one of the guys at one of these awards show reminding the

audience that every great movie begins with a great script but we also have a

lot of lousy movies that probably started with a pretty great script but

all of these things are in the way between the writer and delivering the

writer's vision to the audience. And if we can give writers these tools to

create these things directly and send them to their audience

directly, I think this would be the the biggest boon to to film and TV

maybe since since the invention of the projector. I can hardly wait to see

it and you know I'd worried before that instead of having the broad

popular culture that we had at the dawn of mass media and then for about 30 to

50 years after that, that we you know, now we're in these silos and the silos keep

getting skinnier and skinnier and taller and taller. Well this

disintermediation between the writer and the audience may be able to bring back

the popular culture, the actual broad base culture that we started losing

in the 60s and 70s. Well as we saw from some of the examples

I listed earlier, some of these characters are photorealistic but others

are extremely realistic looking and yet very stylized, they're clearly

not somebody who could ever have been cast.

Hang on Bill, let me throw something in really quick.

My favorite comedic performance of 2017:

Baby Groot!

Yeah, there you go. There you go. Exactly.

Scott, here's what I think is interesting about this, mostly

politically, is that we're not there yet but we're getting there very very

quickly. All of these performances that we saw

earlier are not animators moving lips, frame-by-frame adjusting expressions,

this is facial motion capture, body motion capture, so these are real actors

performing and the computers recording their motions and then translating those

motions on to a digital character and really this essentially got started with

Andy Serkis's amazing work with Gollum back in Lord of the Rings, early 2000s.

But what it means is this, Scott. We're very close to seeing I think the same

kind of revolution in in big ticket entertainment that we saw with that

whole idea of news and opinion when we got started, when the internet finally

had the bandwidth to do video. In other words, for the cost of about five

thousand dollars you can get a pretty good mocap system. Digital animators,

digital sets, digital people. They're not quite there yet but when these things

become photorealistic and a person can produce essentially an epic feature film

in a room the size of this studio and this is not hyperbole by any means, this

is certainly coming. What do you think that does to level the playing field in

terms of getting this kind of content away from these billionaire leftists and

their big studios and out into the people who have differing opinions about

things? I think we live in heady times. I mean it-it's this kind of exciting time

to be alive. I mean the first thing that occurs to me is: Finally! Hurray! There'll

be great opportunities for ugly people who have technical skills. You know you

don't have to - you don't have to have a jaunty jaw or handsome eyebrows to be to

be really at the heart of a star performance in a movie anymore. It's guys

who know how to code. You know, it's people who have actual skills who are

becoming the real stars in Hollywood and I guess we'll have to banish the others

to the stage, where they'll have to perform live in front of people and

learn their craft. The other thing that strikes me is that a computer-generated

character is unlikely to sexually harass his co-stars or the interns on the set.

But not impossible. Yeah not impossible but unlikely. That's why I said just unlikely.

The other thing which is a fascinating notion is, the prominence in recent years of vocal acting

that has, you know you have to actually be a significantly better

actor to pull off some of this stuff-

For all these voices in animated movies. Using a microphone, yeah.

Yeah I mean think of Robin Williams in Aladdin years ago, who really created

that character through the power of his voice and the artists just sort of built

it around Robin William's voice and so you know I think that there are lots of

positive things that come out about. Earlier today I was messing around with

GarageBand on my computer here and it does things that I'm not even, I don't

even have a an inkling of how to do but I have an entire band in my iMac. Yes.

This is my point. I can write a song with a drum line and bass and guitars and put it all

together and if I want to sing on it, I can do that but if I don't I can

completely fabricate all that. So you know I think it is really amazing . We've

said this before on this show but they used to you know, say that we have

freedom of the press in this country for the man who owns one and now in a sense

everybody owns one. wWe have you know freedom to shape the culture for the

person who owns a movie studio and I have one and so will you. Yeah that's

exactly my point. Everyone will be able to own a feature film studio for $10,000

or less. And I think this is what's exciting about it to me. Certainly young

people are trending more and more towards video games, are spending less

and less time and money going to films and more and more time living in the

world of these video games and one of the reasons they become so attractive

is because of what we call these cutscenes which we showed some segments

of earlier where these highly rendered scenes of characters interacting either

with you or with each other followed by some gameplay and then another another

cutscene and so on. So just in a nutshell what I would say is this: if I was a

Hollywood actor I wouldn't be too worried because motion capture requires

acting. As Scott pointed out, it requires exceptional acting and it's a very

difficult kind of acting where you've got a camera directly in front of your

face here and this net and so on. So there's going to be room for a lot

more technicians but these are things that are affordable. Motion

capture systems now $2,000. Facial recognition capture software,

maybe four or five hundred dollars. These are all available. So we'll

still need actors. If I was a movie star on the other hand I'd be a little

concerned about this because a good actor who may just be a real ordinary

looking guy essentially will have the ability to have the features of

whichever particular actor we find most interesting. I will say two things in

terms of a caveat. One of them is that if you get to design your own faces they

tend to all look similar. It's hard to commit to somebody with the

idiosyncrasies that come in from people off of the street. That concerns me

a little bit, sort of the homogeneity of these computerized characters. I suspect

that'll change too. But the final thing I'll say about this is, I think the

people that who have to worry the least are writers. Back in 1980-81, I was and

and I mean we were just getting started with computer games the simplest kind of

you know like branching out, do you want to do this or do you want to do that? And

a theater director teacher who I respected very much named David Shelton

said he was worried that since audiences will be able to make a decision that

basically they won't need writers anymore, that during the course of the

movie at several different key points the audience will vote on what they want

the character to do and therefore you won't need writers anymore and even at

that early time I said Dr. Shelton, I think you're wrong about that one. And

the reason I think you're wrong about that one is because if the audience gets

to decide what the characters are gonna do then they'll always do the right

thing. They'll always do the right thing and they'll always do the thing that we

want them to do, the villains will always be punished, the heroes will

always triumph and it's gonna be as boring as it can be because great story

is when the heroes do something wrong and evil and and the villains have some

humanizing element about them. So those elements will still be here. But to me

it's the democratization of it. It's the idea that already within our fingertips

is the means to produce films that look very much of the quality of Lord of the

Rings or so on and that within the next three or four years certainly we will

all as we now have our own TV studios in our homes and we have our own means

of communication, pretty soon we will all have our own you know enormous Hollywood

movie lots and a hundred and fifty, two hundred, three hundred million dollar

budgets to make these kind of movies and we'll be able to do it if you can talk

your friends into helping you out. It's an interesting world and

we're gonna live to see it. Thanks for joining us, I'm Bill Whittle, we'll see

you next time here with Steve Green and Scott Ott and on Right Angle, made

possible by the paying members at BillWhittle.com.

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