Thứ Năm, 2 tháng 8, 2018

Waching daily Aug 2 2018

raise your standards

the only thing that's gonna make you happy my friend and this year or any

other is to step up it's to raise the standard is to discover what you're

capable of and feel that incredible power of pushing through whatever is

holding you back and get to the other side of more of your true self

don't let this year be like last in a flash there was great Stovall let it be

that way raise the standard it's not what we get that make us happy it slowly

become and what we're able to give because we become one

to change your life that you vacuumed three words worries it sounds raise your

standards being a victim I stopped saying I've gotta wait for good things

to happen that's it I'm gonna cry I'm going to

fight I'm going to work I'm going to press cause I'm going to learn I'm going

to do everything in my powers every single day I'm going to do everything in

my power to become a Victor not affixing winners win and losers

I can't explain it any and a new brand of culture

culture what does it take to successfully create a lasting change in

your life to not only have a new year's resolution

you fall to log and really have a lasting change the secret is progress

getting things not gonna make you happy that's good news in a tough economy it's

good reminder doesn't matter what you get doesn't matter whether it be money

or opportunity all those things might excite you for the moment no even a

relationship as magnificent may be might be exciting for a while

but if you don't keep growing that relationship wasn't gonna stay excited

progress equals happiness and a Keathley progress on a regular basis we feel

alive and that's why the beginning of the year we get this thing like okay I

got this fresh start I can really do what my soul desires I can expand I

could grow I can improve I can change or maybe better than change I could

progress

Mira said he let you down until you get to that point you let you guys get that

were he not brave enough you wanna put it on somebody else the reason why I'm

not successful it feels a lot bought as the applicant shows up in the mirror and

said I'm not getting up on time I'm not going to work on time I'm not working

it works I went leader

I have said I have values I value myself cenotes been you 120% what those do is

that's the problem

you're always gonna blame other people you always know you want to hold other

official to the fire but you're not holding yourself to the fire

give me to tell you no more TVs no more snacks

no more desert no one knows we worked it out now don't no more outs of all that

right now not know I can't imagine you like that you need to tell you that you

owe me some you want you're so funny we want people to make guarantees to us

but we're not willing to make guarantees blood cells and is it gonna be

successful in life yeah it'll go from good to great you

gotta get to a point where you go from now the birth what does that mean action

For more infomation >> Raise Your Standards - Motivational Videos For Students 🔺 - Duration: 3:52.

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Sofia The First - The Silent Knight Part 1 | Top Cartoon For Kids & Children - Duration: 3:49.

♥ Thanks so much for watching!

All right

With my new family and it's all that jumper royalty a whole enchanted world

You

If anything only some incredible dueling by the best Knights in the kingdom

Here sir Bartleby, aren't you I can't believe I'm meeting my favorite Knight. I'm your biggest fan. Ah

That was rude he didn't say one word to you that's because sir Bartleby is the Silent Knight

No one's ever heard him talk but everyone knows he's the bravest knight in the kingdom. Ah, I see the Knights have arrived

Why are they all here? Is there going to be a jousting match?

Actually James they're here to prepare for the shield of Valor ceremony tomorrow. What's the shield of Valor?

It's a special award. We give to someone for being very brave. Which Knight is getting it daddy

Nutty nights your aunt Tilly that's who

I hope he doesn't hurt yourself. I worry more about the night

Umbrella hi there baby, brother. Oh, I mean King baby brother. Hello

Terry oh it's so nice of you to have me over but really there's no need to make a fuss. Of course

There is Tilly you tamed the dreadful dragon of Dashwood. That's why your aunt is getting the shield of Valor

whoa

I know right very impressive but turns out that dragon wasn't so dreadful after all just really nervous

So I taught him how to knit and he calmed right down you taught a dragon how to knit. Uh-huh

Absolutely. He made me these scarves

they look very

what they are once for me and once for the handsome adventurer of my dreams if I ever made him, oh

Don't worry Tilly. You'll find that special someone and he'll be great

Just like you Oh, that'll be whiz-bang. But enemy time two scarves for me

The trumpets if you'll excuse me

Esteemed Knights of enchancia. It is time to rehearse the procession for tomorrow ceremony to your horses

Oh, what a great idea. I think I'll go for a ride, too

Tilly shouldn't you be facing forward then? How will I see? What's behind me?

For more infomation >> Sofia The First - The Silent Knight Part 1 | Top Cartoon For Kids & Children - Duration: 3:49.

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"This is a fight for our daughter": Mollie Tibbetts' family announces reward to bring her home - Duration: 22:09.

For more infomation >> "This is a fight for our daughter": Mollie Tibbetts' family announces reward to bring her home - Duration: 22:09.

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BioBits: Low-cost education kits for molecular and synthetic biology - Duration: 5:48.

So usually, what I do in the lab is I grow a bunch of E. Coli and I give the

E. Coli DNA and the E. Coli cells take the DNA and give me my protein back,

but we don't want to bring live bacteria like E.coli into classrooms.

To engineer Biology, you need complicated equipment,

you need fancy labs.

And as a result, most middle schools, most high schools,

and many colleges are not actually appropriately

equipped in order to teach kids the basics of synthetic biology.

You can imagine these schools are

struggling with STEM funding already and now you're asking

them to basically have all the equipment they need for

a BL1 lab and that includes things like freezers,

refrigerators, incubators that shake.

And one of the things we really set out to do in these bio-bits papers, both bio-bits bright,

and bio-bits explorer is to kind of change that paradigm.

We're creating essentially low cost educational kits

that could be used in a classroom setting for less than $100.

What I did is I took all the machinery that we need to build the proteins,

out of the cells, and put them into these little tubes.

So, we can actually make proteins using

these little pellets without having to grow E. Coli.

Now at a high level what we've done is create

the synthetic biology equivalent to the old chemistry kits.

They're inexpensive, easy to use, easy to store,

can be conducted actually in more or less any room,

and the nature of the kit is the idea that you can freeze dry cell-free extracts.

And what that means is you rip off the cell wall and you collect the guts of the cell.

You can kind of think about that like taking a car and you open the hood and you take

the engine and you put it over here and so what

we had have done is we've taken the engine out of a cell.

Like the ribosomes, the amino acids,

that kind of thing and put it into

a separate solution and if we just add the DNA to that solution,

transcription and translation will happen and

you'll get your protein output.

So we're going to add DNA to

these little pellets and then we're going to put them in our little warming incubator.

So we have the BioBits bright kit, where we use

these freeze-dried cell-free reactions to synthesize fluorescent proteins.

And this allows educators to teach components such as the central dogma:

DNA goes to MRNA goes to proteins.

So for example in one of our labs,

students take an eight-well strip of

these freeze-dried cell-free reactions and by just adding different amounts of DNA,

they show that they can synthesize

different amounts of fluorescent proteins in our test tubes.

In our second lab, we give students a 96-w ell plate of

freeze-dried cell-free reactions and we then

challenge them to build their own in vitro synthetic program,

which in their case means painting a picture with these fluorescent protein reactions.

They can make a rainbow, a periodic table,

and that allows educators to start to talk

about how synthetic biologists might control biology.

So you guys made fluorescent proteins.

Yay!

While the bright kit focuses on expression of fluorescent proteins,

the explorer kit introduces a number of new modules that go

beyond just simple fluorescent protein expression.

Showing that we can do other outputs as well,

such as smells, tactile-based hydrogels,

and the fruit sensors.

You remember why we are adding the soap?

To help break the cells. To bust open the cells.

A really popular biology experiment that teachers do

now is the fruit DNA extraction experiment.

You basically mash up the fruit and you extract

the DNA from it and that's the end of the lesson right there,

but with the cell-free sensors now, you can add on to that.

It actually detect if something is a banana or something is a kiwi.

You can really tell that is a banana.

So the sensor could tell the difference

between all these different fruits and all it's always based on the DNA.

That's really cool.

So for the tactile outputs,

we have the students express enzymes and

these enzymes are able to convert peptides into hydrogels.

Woah, this is cool!

For the smell-based outputs,

we are able to express enzyme called ATF1 and ATF1 is able to

convert Isoamyl alcohol into Isoamyl acetate which is another word for banana oil.

That's so cool. It smells like bananas.

You know, our effort has been done in

very tight collaboration with Northwestern University, Mike Jewett's lab.

Our team has included

really talented grad students and postdocs from MIT and the Wyss institute.

So from the outset,

we engaged as many educators as we could both in the university level as well as outside.

Mike Jewett's team actually already has

integrated and tested their kits in the Chicago school systems.

We actually put these reactions into the hands of K12 teachers and students.

Had them run them. They had never seen these reactions before.

It was their first time running

the experiments and we showed that they worked and that actually

that their results were comparable to experiments that I set up.

It's often times those hands on opportunities where you really

get to touch the science that can be transformative.

I think that that's what we hope these kids are.

We want them to be open access.

We want everyone to be able to engage in them.

And it would be incredibly satisfying to see if we inspired a small number if

not a large number of kids to consider

careers in biomedical research as a result of these kits.

For more infomation >> BioBits: Low-cost education kits for molecular and synthetic biology - Duration: 5:48.

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Michelle Dy Apologizes for Stealing 'Jeffree Star Approved' | Heavy.com - Duration: 4:51.

Michelle Dy Apologizes for Stealing 'Jeffree Star Approved' | Heavy.com

Michelle Dy has been accused of stealing beauty vlogger Jeffree Star's phrase "Approved." On August 1, Star posted a video on his Instagram story of stealing his phrase "Approved," which Star says is copyrighted in the U.S.

Star says in his video that Dy, 26, is "not known in America." Star goes on saying, "I knew I didn't invent the word 'approved' but girl, that's been my thing for two years now.

It's trademarked on my merch.

Don't try me." Star did not name Dy in his video, saying he did not want to give more attention.

Dy came forward to identify herself as the YouTuber Star was talking about saying in a Facebook statement, "Recently, I uploaded 2 new videos in my youtube channel which was the "MD Approved New Series" inspired by Jeffree, while it was clearly stated in the description box in the 2 videos that these new series in my channel were Pinay version and inspired by international YouTubers, I was unaware that this "Jeffree Star Approved" series is copyrighted in America.

I would like to take this opportunity to sincerely apologize to Jeffree Star if in any way or another, I may have violated your rights from the use of your trademark.

Videos from my channel has been deleted already and rest-assured that it will not happen again.

Again, I am sorry.".

Dy goes on to say that she believes a "mistake cannot be corrected with another mistake.

Online records show that Jeffree Star Approved is not a registered trademark in the U.

Despite the deletion of Dy's 'Approved' video, at least one user took a screenshot of Starr's comments on Dy's YouTube video.

The comment reads, "You're full of complete s***.

Stealing my 'Approved' series and trademarked title is pathetic… but that's what boring unoriginal people do.

My lawyer will reach out to your shortly.

'Jeffree Star Approved' is copyrighted in America.

According to her YouTube channel, Dy boasts 1.3 million followers.

Meanwhile, Jeffree Star has 8.6 subscribers on his channel.

On her Instagram page, Dy has 654,000 followers.

Dy began vlogging and blogging in 2012.

Dy has described Michelle Phan has being her inspiration.

It's unclear if Star's lawyer has reached out to the vlogger.

In a April 2017 interview, Dy explained the importance of keeping up with correspondence saying she plans her week "based on [her] email." Dy goes on, "I make sure I get them out of the way first before I move on to my commitments.

I cannot do next activities without finishing the first one." Dy says the best way to start the week is by, "Opening and responding to emails.".

  Thinking of a new video concept while dreaming for another beach trip.

For more infomation >> Michelle Dy Apologizes for Stealing 'Jeffree Star Approved' | Heavy.com - Duration: 4:51.

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For more infomation >> HOW TO DRAW HITMONLEE | Pokémon Drawing and Coloring for Kids | Blabla Art - Duration: 10:16.

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Police Nabs Love Potion Maker in the Philippines for Extortion - Duration: 0:59.

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Part 3 - Healthy Living for Life - Why Vanishing Diseases Are Making a Comeback - Duration: 7:59.

- Welcome back.

The anti-vaccination movement is playing a big role in the resurgence of diseases that

can be prevented by vaccines.

Dr. Holzman and Stacey Anderson are still with us.

That's great.

So I'm gonna go to you, Dr. Holzman.

We talked about vaccine hesitancy before the break.

How do you move forward with messaging to really get more people to immunize?

- I like that you used the word hesitancy 'cause sometimes they put 'em all into this

anti-vaccine movement and a lot of it is hesitancy.

There's a great article in the Atlantic by Julie Beck and I've stolen from her, but I

think she really does it well to categorize us into four different types of people.

One, she talks about the complacent.

We don't see the diseases around us all the time anymore so we're not always in a hurry.

We're not against the vaccine by any means, but it's like, you know, I can't to the doctors

this week to get, I'll get it next week and you know it just gets put off and so there's

that delay and delay and delay and so we see people miss opportunities to get vaccinated

and be up to date with their vaccines and see this with children too.

The other one would be the inaccessible and I think that happens in some of the areas

that this group goes to where it might be a long drive to get to a provider that can

give the vaccine or the cost and stuff like that.

The ACA has helped with that, the Affordable Care Act, but that's another reason that people

might not get vaccines, so we need to encourage the importance of that and also give them

ways to try to decrease those obstacles.

This next person would be the ones that are real contemplative, I mean, they are the ones

that have calculated everything.

We call them the calculators.

They've sat down and go, "Well, we haven't seen polio" "in this country in a long time."

"So while there's very, very little risk," "I think I will not get my kid vaccinated"

"because everybody else is vaccinated around them."

The wrong problem is that too many people start doing that, these diseases are appearing

right away and then we do have these problems.

The last one is the group that's just completely unconfident.

They might be not trust government, they might not trust doctors, they might not trust the

pharmaceutical companies or whatever.

Those people are really gonna be hard to switch over and I will still talk with them and give

them my information and listen to them with respect when they come in, but I realize the

chances that they're gonna change over is probably very little unless sadly one of their

children gets the disease, which we highly hope doesn't ever happen or the other area

is their friends and families around them really convince them and that does make a

difference, people that they have built trust with and hearing it from them so it's good

for people that even believe in vaccines to talk about the importance to those around

them.

- So clearly the need for multiple messaging.

- Multiple messaging and a lot of listening, respecting what other people have to say,

too.

- Absolutely.

So I'm gonna turn to Stacey.

You both work for the Montana Department of Public Health and Human Services, we know

that, and I understand that there is a rather famous individual from Montana who's responsible

for a lot of what we see positive about vaccines, so Stacey, tell us about Dr. Maurice Hilleman.

- Right, so Dr. Maurice Hilleman actually is a native of Mile City, Montana, which not

too many folks know about you know when we learn about the history of vaccines, he's

not one of the names that usually pops up, but he has contributed to the development

as well as the safety and efficacy studies of more than 40 vaccines in his career and

has been credited with saving millions of children's lives.

His body of work has been very powerful and very positive for vaccinations.

An interesting story about him is that he was one of the folks that worked on the MMR

vaccine for measles, mumps and rubella.

His daughter came down with the mumps and he was a scientist working in a lab and so

he took a swab of his daughter's cheek and then grew up the mumps virus that she was

infected with and used that virus to improve the preparation of the MMR vaccine and that

strain is called the Jeryl Lynn strain and it's still in the vaccine that we use today

to protect our children.

And to even make it more of an interesting story, years later, his younger daughter was

one of the first kiddos that was inoculated using this new preparation of the vaccine

and there's an iconic photo out there of the two siblings helping each other through that

process of getting vaccinated.

So we credit him with the positive things that have happened to protect kids against

these diseases that were terrible many, many years ago.

- Another example of a Montanan making a big difference

- absolutely.

- in healthcare, right?

- Yes.

- Let's switch to Dr. Holzman.

So really interesting history, but let's talk about the future.

What does the future hold for vaccinations for all of us?

- Yeah, I'd love to see some more studies and some more vaccines come about because

I think they're huge successes.

But we're seeing things with new diseases.

They confirmed we now have an Ebola vaccine that's going through trials at this point

in time, but they're actually using it right now in the Congo with an outbreak that's going

on there.

Hopefully someday we'll get an HIV vaccine, so there's these infections.

We now have therapeutic vaccines.

This is a little bit different.

So the first vaccine that came out like that was the hepatitis B vaccine.

This is a vaccine going at a virus, but we know that virus has a big effect on having

things like liver cancer so trying to prevent that or HPV trying to prevent cervical cancer,

penile cancer and other issues there, so we have that aspect coming about.

The other thing that we've seen a lot with is some work and I think Stacey and I would

both love to see this is a universal flu vaccine so we don't have to try to guess what's coming

next year and put the strains in there, but finding an antigen aspect on that that we

could give once or once with a booster and then you'd be covered for flu for the rest

of your life.

And then the last thing I think is some of the new areas of how do

we give those vaccines.

We have oral vaccines, we have nasal vaccines, but the newest one that's coming about is

what we call microneedles and it's like a little stamp with the antigens on it and they

just push it on there and then they pull back and the antigens stay there and all the sudden,

you start to get a response to that, so wouldn't that be great not to see your child be screaming

when getting those shots and being able to feel that way, so that'd be awesome.

- I will look forward to that day for sure.

Thank you both so much for being with us today.

And thank you for watching.

Be sure to join us again next week.

Until then, stay fit, stay well and stay healthy for life with Healthy Living for Life.

Take care.

- [Announcer] Healthy Living for Life is brought to you by Mountain-Pacific Quality Health.

We'd love to hear from you.

If you have suggestions for future programs, visit our website at mpqhf.org or call us

at 406-443-4020.

You can also catch us on YouTube by visiting our website and clicking on the YouTube icon.

Special thanks to Fire Tower Coffee House and Roasters.

Production facilities provided by Video Express Productions.

For more infomation >> Part 3 - Healthy Living for Life - Why Vanishing Diseases Are Making a Comeback - Duration: 7:59.

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Healthy Living for Life - Why Vanishing Diseases Are Making a Comeback (Full Version) - Duration: 23:01.

- [Narrator] Living longer living healthier living better than ever before.

Welcome to Mountain-Pacific's Healthy Living for Life, a weekly series that gives you the

information, education and expert insight you need to become an active participant in

today's ever-changing healthcare climate.

Here now is today's program host.

- Diseases we thought were gone, mostly gone or under control by vaccinations are making

a comeback.

Over the past decade, vaccine-preventable diseases have gained a new foothold, posing

a threat to our country's population health.

Welcome to Healthy Living for Life, a show dedicated to helping you do just that.

I'm your host Sara Medley.

Today we talk about the effects of the anti-vaccination movement.

Stay with us, we'll be right back.

- Welcome back.

Though vaccination has led to a dramatic drop in cases of certain contagious diseases in

this country, vaccine-preventable infections are still a threat to us and our communities.

Joining us this morning is Dr. Greg Holzman and Stacey Anderson from the Montana Department

of Health and Human Services.

Thank you both for being with us.

- Thank you.

- Thank you.

- I'm gonna start with you, Dr. Holzman, can you tell our viewers about your credentials?

What kind of a physician are you?

- I hope a good one, but I'll add in the credentials I have is I've actually done two residencies.

I'm boarded in two areas.

One is in family medicine and one is in preventive medicine, which is a lot of public health

and got my master's in public health through that residency program also.

- [Sara] Excellent.

How long have you been in Montana?

- This time around it's just about three years.

My first job out of residency for my family medicine residency was actually on the Blackfeet

Indian Reservation and that was the first time I'd ever touched foot in Montana.

- Excellent, thank you.

How about you, Stacey?

Talk about your background.

- So I have a background in microbiology, which is contagious disease and the study

of those diseases and then I have a master's in public health as well, from Westminster

College in Utah, and I've been in this position for about seven years now.

- Excellent.

Alright, now I'm gonna switch back to you and ask you to talk about vaccinations and

why are they so important?

- You know a lot of times when I talk about those, I like to talk about the history, because

it's just so amazing when you look at this and I can give you a lot of numbers.

Let's use measles as an example.

If you look at measles, the number of cases in the United States before the measles vaccine

was about four million a year, and then the measles vaccine came around in 1963.

Or if you look worldwide, it was estimated that there was about 2.6 million deaths a

year from measles prior to that vaccine.

Sadly, that vaccine has not gotten all around the world and we haven't gotten the immunizations

as well as we want, but the deaths from measles has decreased quite a bit and it's down at

80,000 to 90,000 a year, so still a lot, but it kind of lets us also here in the United

States, where we rarely see measles cases, just understand that this is a serious disease.

And I could give those kind of statistics for all sorts of different diseases and what

a difference vaccines have made in that.

What I would say is, seeing the decrease that has happened, I often like to tell stories

along with it because the numbers sometimes get hard to understand when you're talking

these kind of things and I think that often times my grandparents who were born 1890,

my grandmother was born and my grandfather was born, grandfather and grandmother on the

other side in 1908 and 1905.

Their average life expectancy at that time was 47 years.

That was at the turn of last century, going into the 20th century.

By the time we got to 2000, the average life expectancy in the United States was 78.1 years.

You have this huge increase and you think about well that's because all these things

that happened in medicine.

We got antibiotics, we can do better surgeries, we have insulin now that wasn't around beforehand,

but actually when you look at the data and everything, about 25 of those years are due

to public health.

And the CDC put out this great, CDC is the Centers for Disease Control and Prevention,

put out this great tribute at the end of last century called The 10 Greatest Public Health

Interventions in the Last Century that had the effect on that and vaccines is one of

those.

It's a big one in there.

There's things from workforce, decreased workforce injuries and deaths and the numbers are very

inspiring to see what a difference that made.

Vaccines are probably, two things, one is the control of infections disease that we

got much better at trying to decrease infection, like with refrigeration and just proper handwashing,

pasteurization, how many deaths happened from outbreaks from unpasteurized milk prior to

that.

These type of things going on and then to get the immune system to get your own body

to fight a disease before you ever get exposed to it and that's where we see some great changes

with vaccines and you see things where you see numbers of measles cases decrease by 99

percent or even something in my lifetime has been haemophilus influenzae vaccination that

has gone down, a 99 percent of decrease in those infections or some diseases that we

don't see anymore at all in the world, like small pox, or even in the United States like

polio and hopefully gettin' close to eradicating that in the world, but still struggling with

a few countries where it shows up.

So made a huge difference and I could go on and on on that.

- That is amazing.

Well, let's switch to Stacey and Stacey, can you talk about how vaccines changed the landscape

for communicable diseases in Montana?

- Sure, so a good example to kind of take from what Dr. Holzman was saying is looking

at mumps.

Mumps is one of those communicable diseases that is currently protected by the MMR vaccine.

Measles is one of the other components.

Mumps is generally sort of a, or was considered a childhood disease.

It's usually pretty self-limited in that you recover fairly easily but can have some side

effects and some consequences including things like deafness and inflammation of the brain,

very rare, but it can happen.

Prior to the introduction or the recommendation to give that dose of MMR against mumps, we

would see hundreds and hundreds of cases in Montana and then within the first few years

after that first dose was recommended, the number of cases dramatically fell.

And then once the recommendation was given to add a second dose of MMR for all kids,

it even fell even smaller.

We have very few cases since then, pretty much sporadic activity.

Every once in a while, you'll see an uptick of these things, but generally speaking, it's

had a significant impact in the number of cases that we've seen in Montana in the intervening

years.

Another example that Dr. Holzman mentioned was haemophilus influenzae.

This is another bacterial disease that affects babies.

Since the introduction of that vaccine, we've seen very, very few cases so it's been a positive

impact.

- Oh, that's wonderful.

Great, well, we need to pause here and take a quick break, but coming up next, how did

the anti-vaccination movement start and are there really risks associated with the MMR

vaccine?

We'll talk about that and much more right after these messages.

Stay with us.

- Welcome back.

In the late 1990s, a study linked childhood vaccinations to autism.

Even though an investigation into the study proved the findings wrong and even though

the doctor who led the study had his license revoked for serious professional misconduct,

the study planted seeds of fear and set off an anti-vaccination movement.

Dr. Holzman and Stacey Anderson from the Montana Department of Public Health and Human Services

are still with us.

So, we're back.

- Yeah.

- [Sara] Gonna go to you, Dr. Holzman.

Let's talk about that anti-vaccination movement.

If vaccinations are so effective, why do people resist getting them?

- Yeah, it's interesting.

Since the first vaccine came about, which is actually 1797 was when the small pox vaccine

was first figured out, there's always been an anti-vaccine movement and that has gone

on, we just recently did work on the pandemic flu of 1918-1919 here in Montana and during

that aside thing, we saw that there was a big uproar about small pox vaccine in Butte,

Montana, of a group of people that went to the board of health.

It said no they had to get their vaccines.

It went all the way to the state board that supported them and the vaccines were given.

This issue has already gone all the way to the Supreme Court in 1905 about individual

liberties versus community protection and again, vaccines were supported in that ruling

of Jacobson versus Massachusetts.

So I think the issue is that's been around but I think the point even more that we need

to demystify in the myth is that it's big because if you look at a Pew survey that was

done in 2017 showed that 88 percent of Americans believe that vaccines are safe and the benefits

highly outweigh the risk to get vaccinated.

If we look at our own data in Montana that we'll see in many of our areas, polio vaccine

in kids about 88 percent.

We see things, you know, these areas that we see this constant increase in the numbers

of people getting vaccinated, so there is a small percentage and there's different reasons

that people choose not to get vaccinated or delay vaccinations, but overall, the movement

is actually fairly small and most people see and look at the data to say, "This is a good

thing."

- So let's switch to you, Stacey.

And tell us about that Wakefield study from the 1990s.

You know, why did it cause so much concern about the MMR vaccine?

- So the issue with the Wakefield study was Dr. Wakefield and some of his co-authors did

this study that was looking at young children who were developing signs of autism around

the same time that they were given their first dose of the MMR vaccine.

And so, you know, in science, one of the things that we have to look at is you can make a

connection like that, but can you truly establish what's called a causal relationship, meaning

does that event truly cause the outcome?

And the problem with that study is that that was the conclusion that Wakefield wanted to

draw, that people who were getting MMR vaccine were developing autism.

And in fact, that was incorrect, and as you said earlier, that study was eventually revoked,

it was reviewed, found to be that some of that data for that study was not only a very

small number of individuals, which is very hard to study.

You need larger samples, basically, to study something well, but also the data was falsified

and future studies could never reproduce that same result.

In fact, future studies have shown that there is no link between the MMR vaccine and the

development of autism and so as you mentioned, Dr. Wakefield lost his license, the study

was pulled back and discredited.

I'm here to say there is no link, there is no link between receiving an MMR and the development

of autism in the scientific body of knowledge.

- So to follow up on that, he was discredited, the study was discredited, yet there are still

naysayers who are not vaccinating, so why would that be all these years later?

- Well, it did take some time for that study to be discredited.

There was quite a period of years between the study's results and the following retraction

of the study.

That resulted in a lot of discussions with people talking about how these were definitely

connected and of course if you're a parent and you're seeing this happen, you know, it's

scary.

You wanna know why your child developed these symptoms and you wanna make sure you educate

people around you as to well, this is what happens, so I don't want it to happen to you.

A lot of that kind of continued on until the study was officially retracted and then sometimes

it's hard to change those modes of thinking all these years later.

- I think there's some other aspects that I would add onto what Stacey talks about here

is the sense that one, autism is scary and we're seeing it go up in numbers and we wanna

understand why.

I think it's sad that we continue to pay so much time in trying to revoke this kind of

going over and over again on that where we should be putting it towards trying to understand

autism and see if there's ways we could do better on prevention and better treatments

of that.

The other thing that I think, social media probably has an effect, too.

I mean we all go to the sources that we feel best and so sometimes we will go to a source

that I use the word "data" and I use that loosely that we have the data that supports

our pre-held belief instead of being able to continually to look at the bigger picture

and look at the other side's viewpoints to come to those answers.

- So we've got about 30 seconds left and in that time period, can you briefly describe

the types of people that shouldn't get vaccinations?

Who are they?

- It's very minimal, but there are sometimes that you'll find a medical reason not to get

vaccinations.

Just to give you an idea, in Montana, about point four percent of children have a medical

reason and that might be because of an allergy that they have to a component within the vaccine

or it might be that they have a decreased immune system or reasons that they can't get

a specific vaccine.

Sometimes it's so that they can't one or two different vaccines, but they can get the others,

so talk to your provider and go through that.

- We need to pause here and take a quick break, but coming up next we'll talk more about the

impact the anti-vaccination movement is having on public health and what's being done to

overcome it.

Don't go away.

- Welcome back.

The anti-vaccination movement is playing a big role in the resurgence of diseases that

can be prevented by vaccines.

Dr. Holzman and Stacey Anderson are still with us.

That's great.

So I'm gonna go to you, Dr. Holzman.

We talked about vaccine hesitancy before the break.

How do you move forward with messaging to really get more people to immunize?

- I like that you used the word hesitancy 'cause sometimes they put 'em all into this

anti-vaccine movement and a lot of it is hesitancy.

There's a great article in the Atlantic by Julie Beck and I've stolen from her, but I

think she really does it well to categorize us into four different types of people.

One, she talks about the complacent.

We don't see the diseases around us all the time anymore so we're not always in a hurry.

We're not against the vaccine by any means, but it's like, you know, I can't to the doctors

this week to get, I'll get it next week and you know it just gets put off and so there's

that delay and delay and delay and so we see people miss opportunities to get vaccinated

and be up to date with their vaccines and see this with children too.

The other one would be the inaccessible and I think that happens in some of the areas

that this group goes to where it might be a long drive to get to a provider that can

give the vaccine or the cost and stuff like that.

The ACA has helped with that, the Affordable Care Act, but that's another reason that people

might not get vaccines, so we need to encourage the importance of that and also give them

ways to try to decrease those obstacles.

This next person would be the ones that are real contemplative, I mean, they are the ones

that have calculated everything.

We call them the calculators.

They've sat down and go, "Well, we haven't seen polio" "in this country in a long time."

"So while there's very, very little risk," "I think I will not get my kid vaccinated"

"because everybody else is vaccinated around them."

The wrong problem is that too many people start doing that, these diseases are appearing

right away and then we do have these problems.

The last one is the group that's just completely unconfident.

They might be not trust government, they might not trust doctors, they might not trust the

pharmaceutical companies or whatever.

Those people are really gonna be hard to switch over and I will still talk with them and give

them my information and listen to them with respect when they come in, but I realize the

chances that they're gonna change over is probably very little unless sadly one of their

children gets the disease, which we highly hope doesn't ever happen or the other area

is their friends and families around them really convince them and that does make a

difference, people that they have built trust with and hearing it from them so it's good

for people that even believe in vaccines to talk about the importance to those around

them.

- So clearly the need for multiple messaging.

- Multiple messaging and a lot of listening, respecting what other people have to say,

too.

- Absolutely.

So I'm gonna turn to Stacey.

You both work for the Montana Department of Public Health and Human Services, we know

that, and I understand that there is a rather famous individual from Montana who's responsible

for a lot of what we see positive about vaccines, so Stacey, tell us about Dr. Maurice Hilleman.

- Right, so Dr. Maurice Hilleman actually is a native of Mile City, Montana, which not

too many folks know about you know when we learn about the history of vaccines, he's

not one of the names that usually pops up, but he has contributed to the development

as well as the safety and efficacy studies of more than 40 vaccines in his career and

has been credited with saving millions of children's lives.

His body of work has been very powerful and very positive for vaccinations.

An interesting story about him is that he was one of the folks that worked on the MMR

vaccine for measles, mumps and rubella.

His daughter came down with the mumps and he was a scientist working in a lab and so

he took a swab of his daughter's cheek and then grew up the mumps virus that she was

infected with and used that virus to improve the preparation of the MMR vaccine and that

strain is called the Jeryl Lynn strain and it's still in the vaccine that we use today

to protect our children.

And to even make it more of an interesting story, years later, his younger daughter was

one of the first kiddos that was inoculated using this new preparation of the vaccine

and there's an iconic photo out there of the two siblings helping each other through that

process of getting vaccinated.

So we credit him with the positive things that have happened to protect kids against

these diseases that were terrible many, many years ago.

- Another example of a Montanan making a big difference

- absolutely.

- in healthcare, right?

- Yes.

- Let's switch to Dr. Holzman.

So really interesting history, but let's talk about the future.

What does the future hold for vaccinations for all of us?

- Yeah, I'd love to see some more studies and some more vaccines come about because

I think they're huge successes.

But we're seeing things with new diseases.

They confirmed we now have an Ebola vaccine that's going through trials at this point

in time, but they're actually using it right now in the Congo with an outbreak that's going

on there.

Hopefully someday we'll get an HIV vaccine, so there's these infections.

We now have therapeutic vaccines.

This is a little bit different.

So the first vaccine that came out like that was the hepatitis B vaccine.

This is a vaccine going at a virus, but we know that virus has a big effect on having

things like liver cancer so trying to prevent that or HPV trying to prevent cervical cancer,

penile cancer and other issues there, so we have that aspect coming about.

The other thing that we've seen a lot with is some work and I think Stacey and I would

both love to see this is a universal flu vaccine so we don't have to try to guess what's coming

next year and put the strains in there, but finding an antigen

aspect on that that we could give once or once with a booster and then you'd be covered

for flu for the rest of your life.

And then the last thing I think is some of the new areas of how do we give those vaccines.

We have oral vaccines, we have nasal vaccines, but the newest one that's coming about is

what we call microneedles and it's like a little stamp with the antigens on it and

they just push it on there and then they pull back and the antigens stay there and all the

sudden, you start to get a response to that, so wouldn't that be great not to see your

child be screaming when getting those shots and being able to feel that way, so that'd

be awesome.

- I will look forward to that day for sure.

Thank you both so much for being with us today.

And thank you for watching.

Be sure to join us again next week.

Until then, stay fit, stay well and stay healthy for life with Healthy Living for Life.

Take care.

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