Thứ Năm, 30 tháng 8, 2018

Waching daily Aug 30 2018

Baby, are you full?

No?

Haha, what are you doing?

Naidou?

I am giving Naidou a manicure, she is so cute and falling a asleep.

For more infomation >> When the monkey is asleep, the owner gives her a manicure - Duration: 1:18.

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Shaunie Is Not Happy Evelyn Lozada Invited Jennifer Williams | Basketball Wives - Duration: 1:53.

I have something to tell you.

What? This group and secrets, dammit. What's the new one?

No, well that's why I'm telling you,

because I don't want it to be a secret.

You promise not to get mad at me?

Evelyn ... can't.

So, I had a conversation with Jennifer.

I invited her here.

Oh no, the hell you did not.

I did.

So ...

I feel like you guys need to have a conversation

without Tami there, just you and her.

Same thing for Malaysia, just them two.

And if you guys leave here feeling the same way, then fine.

I'm out of it.

I don't know where this clinging to Jen is coming from.

I don't know if it's just she's genuinely

so loyal to Jen and loyal to me,

that she just wants it all to work out, or is this because

Evelyn feels like Tami plotted this?

I don't know.

So, this bitch is about to come all the Amsterdam

to have a conversation I could have had her with in LA,

that I wasn't gonna have in LA

and still ain't having here in Amsterdam.

I think she really wants to make it right.

I feel like Shaunie should hear out Jennifer.

I'm sure Tami's called, had her ear,

tried to explain the (beep).

I feel like Jennifer should have the same opportunity.

I could give a (beep) what Jennifer wants to do.

You have really affected my life,

even if it's for moment, over some bull (beep).

I don't have anything to talk to her about.

But if her ass wants to travel

all the way to Amsterdam to get told,

"I don't have (beep) to say to you," so be it.

You set your friend up.

For more infomation >> Shaunie Is Not Happy Evelyn Lozada Invited Jennifer Williams | Basketball Wives - Duration: 1:53.

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This is the Bloodwork You Should Get for Iron Overload | Chris Masterjohn Lite #64 - Duration: 7:35.

This is how to use an iron panel, serum

ferritin, and transferrin in order to

assess your iron status.

Hi, I'm Dr. Chris Masterjohn of

chrismasterjohnphd.com. This is

Chris Masterjohn Lite,

where the name of the game is

"Details? Shmeetails. Just tell me what works!"

And today we're going to talk

about blood work for managing iron status.

There's a whole lot to unpack in

the topic of iron that I'm not talking

about today, and that includes anemia, and

that includes many medical disorders.

What I want to talk about today is how

to make sure that you're not suffering

from iron overload using these iron

tests, and in particular why it's

important to look at ferritin and

transferrin on top of the iron panel

when looking at this. If you look on the

screen, you'll see the list of iron tests

that I got for my most recent blood

analysis. We'll look at the numbers in

the next video.

We have iron and TIBC. TIBC means

total iron-binding capacity, and that

breaks down into TIBC, UIBC, which is

unbound iron-binding capacity, iron, and

iron saturation. Then as separate tests,

I have added on here serum ferritin and

serum transferrin. The things that we're

really interested with these tests are

serum ferritin, which is a marker of your

long-term iron storage, and transferrin

saturation, which is not the same as

serum transferrin. It's the number of

transferrin molecules in your blood that

have their iron binding sites bound to

iron. Transferrin is your short-term

store of iron, distinct from ferritin,

which is your long-term store of iron,

and together serum ferritin and

transferrin saturation give a good

picture of your short- and long-term iron

status. When you are subject to iron

overload, what happens early on is

transferrin saturation increases above

what it normally would increase to

before ferritin kicks in. Normally you eat

iron, your serum transferrin saturation

goes up, that kicks in ferritin to take some

of that iron and put it in long-term

storage. When you have iron overload

conditions because of a genetic

predisposition, the transferrin

saturation goes up, and it doesn't kick

iron over into ferritin until much later.

If you have a late-stage iron overload

condition, you will see ferritin rise,

and you can see it rise very, very high.

In the iron binding panel, what we're

looking at is measures of iron

saturation, and this is a cheaper

estimate of transferrin saturation. What

they do here is they say, "You know, it's

mostly transferrin in the blood that's

binding iron, so let's just throw iron at

the blood and see how much sticks."

By doing that, you can estimate the total

iron-binding capacity of the blood, that's

how much can stick when the iron is

removed; the unbound iron-binding

capacity, that's how much sticks when you

don't remove the natural iron present in

the blood; and then how much iron is in

the blood, and you can use all this to

estimate the iron saturation, all as a

means of getting a cheaper estimate of

transferrin saturation, which is what

we're really interested in. What we want

is for the transferrin saturation to be

between 30% and 40%. The range that

they give for iron saturation is bigger

than that, 15% to 55%, but when we're

looking for an optimal range, 30% to 40% is the

optimal range. In the case of serum

ferritin, the ranges are controversial,

and the ranges vary from laboratory to

laboratory and over time. In my opinion,

we generally want to keep serum ferritin

between 60 and 150. In cases where

someone has a long experience of being

subject to iron overload, it might make

sense to go under 60, maybe even go

down to 20 or 30. But in cases

where someone's predisposed to anemia,

that's a good reason for trying to keep

it above 60 and maybe even get

towards 100 to 150. Because in one case,

you're trying to drain iron that's been

overloaded out of the body, and in the other

case, you're trying to replete iron

stores, and so it makes sense to be on

the higher or lower end of that

accordingly. For transferrin saturation,

the way that we estimate—the way that

we calculate this when we've measured

transferrin is to take this serum iron,

divide it by the serum transferrin, and

multiply it by 0.79.

Now, you might ask, "Why should you bother with

that if you have already estimated it

with the iron saturation?" And the reason

is that there are other things in the

blood besides transferrin that bind to iron.

Albumin, for example, is the most

prevalent protein in the blood, and it

can bind to iron. And there are studies

suggesting that in some people with iron

overload, iron saturation is often an

underestimate of the transferrin

saturation. And it's the transferrin

saturation that you want between 30% and 40%.

So here's what I would

suggest. Given the fact that measuring

serum transferrin is more expensive than

the iron panel, it does make sense to be

conservative about ordering the test

when you don't need to. But you don't

know if you need to until you order the

test at least once. So what I would do is

at least once or maybe three times, get

all of these measured and compare the

transferrin saturation when calculated

as serum iron divided by serum

transferrin times 0.79

to the iron saturation. If they diverge

consistently, then you probably want to

continue measuring your transferrin

saturation by getting transferrin and

making the calculation as long as you

continue to have iron-related issues

that you believe need to be managed.

If, on the other hand, your transferrin

saturation as calculated that way always

looks like your iron saturation, then I

think you can conclude from that that

iron saturation is a good enough proxy

to use going forward, and going forward,

you can limit this to the iron panel and

to the ferritin.

You can find more details on managing

and monitoring iron status in my e-book,

Testing Nutritional Status: The Ultimate Cheat Sheet.

The audio of this episode was enhanced

and post-processed by Bob Davodian

of Taurean Mixing. You can find more

of his work at taureanonlinemixing.com.

This episode is brought to you by

Testing Nutritional Status: The Ultimate Cheat Sheet.

Everything you could ever need to know

about optimizing your nutrition all in one place.

Easier to find and use than ever before.

Get your copy at chrismasterjohnphd.com/cheatsheet.

Use the code LITE5,

all capitals, L-I-T-E-5.

LITE5 to get $5 off.

All right, I hope you found this useful.

Signing off, this is Chris Masterjohn of

chrismasterjohnphd.com.

This has been Chris Masterjohn Lite.

And I will see you in the next episode.

For more infomation >> This is the Bloodwork You Should Get for Iron Overload | Chris Masterjohn Lite #64 - Duration: 7:35.

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'This is us' behind the scenes special airing on NBC Charlotte - Duration: 1:08.

For more infomation >> 'This is us' behind the scenes special airing on NBC Charlotte - Duration: 1:08.

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Who is accessing MATOD in Australia - Duration: 1:48.

I think when we talk about opioid dependence and who's likely to be affected by opioid

dependence, often because of the media, or different images that are portrayed around

someone that might have a problem with substance use, we have these very negative ideas of

who that might affect.

From much of the research I've done, you know, the average person who's developed a problem

with codeine for example is a 42 year-old woman.

So, someone who looks very much like me, or you, and when I'm talking to health professionals

about this, it's like, the best way to kind of work out what someone might look like is

to probably look in the mirror, because it affects many different people.

The idea that these very stigmatised images that we have of people who might have problems

with substances are just not helpful, and they're not accurate.

What these medications do, is they really reduce those symptoms of opioid withdrawal

and craving, and also often the pain that's associated with opioid withdrawal, and it

doesn't actually make a lot of difference which opioid it was that you were using, so

whether or not the opioid was codeine or oxycodone or even heroin, which is what these treatments

were originally developed for.

But we find, particularly when we look at our treatment statistics in Victoria and Australia

now, that many people who are starting on these medications are doing so because they

were having problems with a medication like codeine or oxycodone and so in lots of areas,

that's actually becoming more common.

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