Thứ Năm, 1 tháng 3, 2018

Waching daily Mar 2 2018

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no more well meeting the totally smothering overprotectiveness looking

dad's number one course Pete and I'm a free man you'll get a degree and the

world will be your clan sorry

like I was saying like college for instance if you want that diploma you've

gotta fix both Isaac's a Maxie you just gotta stay focused it's gonna

be a long time before you see your old man again what maybe Christmas

I'm not taking old stuffed bear to college dad well then hook up something

else poor son I want you know just stunned what is it

this was my father's answer

doughnuts

look like Magellan Fiji you couldn't spell Magellan

gentlemen I welcome you to the first day of the rest of our lives is the one the

only Bradley upper-crust the third

maxie Mexico and assembly line is for assembling

looks like gamma material

oh no no no it's it's alright really you know I'd wager that if you were on a

skateboard oh yes my right-hand man Gama brother tank the pleasure's all mine

baby welcome aboard little tyke your class

the hot guide you want us to be gammas oh you guys you hear that we're gonna be

part of hold on pal I thought you wanted to win well that's

just what we're going to do like you'll find any better competitors than my

teammates they're the real deal Wow nice trick

did they go fetch and play dead too why yes as a matter of fact they do gammas

see I'm giving you the opportunity to join the gamma mu mu fraternity

I like your style Little Miss Mochaccino but I'm busy right now

well I'm dizzy right now from watching your downward spiral is he blowing out

bad vibes in every direction that we are all choking on your secondhand smoke

well we'll defer on you and the gammas your Royal lowness he'll be lucky to be

my towel boy gammas out

well mr. goose so what do you need what is a degree bingo we have a winner

College me well I was there in the 70s I'm too old for that now come on Saul

you're never too old to learn a new trick

so I got fired I guess I lost my focus now I'm gonna get me that college degree

first thing lose the wig what I need to look hip and groovy for college you're

scaring people just think Oh mother here just you and me it's kids severely

affect campus high jinkies yeah and how we gonna whip those gammas

now you mean like his pink slip for showing

don't push it man I talked to him and laid out all the ground rule he's got

his life I've got my life my life my

first class is did too dude thank you so what every day starts with

we can get a head start on our treat Norman's a tricky math lamb is a treat

I'll get us tickets where are you going son

oh yeah well I was just gonna go to you know go to the hi there Miss Marple II

MARPOL Marple my dad needs a library card good oh it would be my pleasure

with respect you'll find these helpful to your library experience are you

kiddin this here the Gilligan's Island fan club seats you get out I love all

that 7e stuff come on guys we're out of here

Oh remember the boogie duck for you Oh Oh Miss Marple oh you can call me sit

yeah Gouri sure so you're free on Saturday what about you and your team I

mean we could practice together and we're them funny outfits and everything

would be a lot of fun dad is fun mr. goof your performance was without a

doubt the most breathtaking have an opening on our team it has got your name

on it buddy I'm not sure you understand the bond between a father and his son

next our team the gammas are the team and they need you more than we do

oh yeah mr. goof the gammas are like way hot man and besides a Oh mr. upper-crust

you can count me in gamma brother goofy let me present you with your gamma mu mu

pledge pin Gallas exit it worked we unloaded my dad

now we can focus winning

make beautiful bongo music together whoa easy boy you're fogging up my car hey

you want to sit with us it is endemic of the current culture that those with

large stature are overlooked except by vultures anyone overlooked such a bundle

of yes miss let's dance

wife takes the child the wife takes the child heigh ho the derry-o the wife

takes the child the child takes the ders

For more infomation >> An Extremely Goofy Movie Best Cartoon For Kids & Children Part 1 - Red Dog - Duration: 14:29.

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EXTRA! My way for making Tattoos - Duration: 5:46.

For more infomation >> EXTRA! My way for making Tattoos - Duration: 5:46.

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Albuquerque high schoolers gather for safety forum - Duration: 0:33.

For more infomation >> Albuquerque high schoolers gather for safety forum - Duration: 0:33.

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Democratic congresswoman voices support for steel tariffs - Duration: 6:54.

For more infomation >> Democratic congresswoman voices support for steel tariffs - Duration: 6:54.

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Ha seokjin!~ words of blessing from you for the new year. [2Days & 1Night-Season 3/2018.02.11] - Duration: 9:39.

Let's go to the sledding slope now.

- To the sledding slope. / - For a wintry landscape.

There might be a grandmother born in 1946.

That would be great.

- Let's go. / - I'm getting in.

We should meet people born in 1982 and 1946.

- I'm hungry. / - Me, too.

Let's pretend to eat tteokbokki with nine dollars.

Let's turn off the camera and eat samgyeopsal.

It's a good idea.

That's amazing.

- We're alone anyway. / - I know.

We're not shooting now.

The camera is on now.

- Really? / - This isn't right.

I'm so full.

(Embarrassed)

It's only 4.4km away? It's close.

Let me see.

When I take a picture of children,

I don't want them to know I'm taking their pictures

so that they will look happy in the picture.

- So you should / - Just take some pictures.

talk to the kids as I take pictures.

Is there a sledding slope here?

(They arrive at the sledding slope.)

Let's set the starting point.

Is the camera on?

Junho.

In one, two and three.

Let's go.

Let's go, fools.

(Laughing)

(Remember the Members, 2 O'clock News)

We're at Ttukseom.

(We're at Ttukseom.)

We will take a picture of a wintry landscape.

With the fashionistas.

This way. Let's go.

This is the wintry landscape of Seoul.

There are a lot of children.

- Look at the snow. / - Look at the children.

Zoom in.

Look. There are a lot of children.

They're having fun.

(A sledding slope in the center of the city.)

Insert.

Insert.

(They try hard to film the scene.)

The staff should come here to film this scene again.

- This is good. / - Good.

He's not shooting it right.

He's not doing it right.

Being a VJ is so hard.

(He gets to experience a demanding job.)

How much is it?

It's six dollars per person.

We don't have money.

(They only have 10 dollars in total.)

- Hello. / - My goodness.

- Hello. / - Hello.

Hello.

- Excuse me. / - It's nice to meet you.

Sir, we are shooting Two Days and One Night now.

We need to take a picture of a wintry landscape.

May one of us get in there and take some pictures?

- You can do that. / - Really?

The rest of us will wait in here, then.

- Please have a seat. / - They have mandarins.

(This was his intention.)

(Who will carry out the mission, then?)

I'll go take some pictures.

(It's Siyoon whose mind is urgent.)

(Running quickly)

(Taking pictures over and over again)

(Siyoon is burning with passion.)

Hello.

(While Siyoon takes pictures...)

- Are you Defconn? / - Yes, I am.

Hello. Say hi to me.

She's running away.

Siyoon, let's go. We don't have time.

Okay.

We don't have time for this.

(While they are busy taking pictures...)

May I take a picture?

(The rest of them are enjoying mandarins.)

I'll have some mandarins.

(Jongmin is collecting evidence.)

Can you please put mandarins in my mouth?

I think he's shooting me.

I'm not.

(Junho has eyes on the back of his head.)

(He pretends to eat it against his will.)

Excuse me, but...

(Meanwhile, Siyoon found the perfect subject.)

This is perfect. They're so cute.

(They took pictures of a wintry landscape.)

- Let's go. / - Let's go.

Hey, who has the money now?

- Joonyoung has. / - Go buy something to eat.

We can eat it in the car.

We'll go buy some food.

You know what to do, right?

Buy some food with nine dollars.

- I know. / - We know what you mean.

(Junho and Jongmin go to buy some food.)

I know we will eat nine dollars' worth of food.

What do you want to buy?

(They arrive at a convenience store.)

The big corn dog looks good.

A big corn dog.

Ramyeon.

We probably shouldn't shoot a video in there.

- In the store. / - Right.

Clap your hands.

In one, two and three.

(They turned off the camera.)

(Taehyun is back in the car.)

Impact detected.

(He checks his microphone.)

(And he replaces the batteries.)

(Kind Taehyun)

Taehyun says we should replace the batteries.

Come here. Let me check the batteries.

We should replace the batteries?

You look like the production staff.

You're so meticulous.

(He replaces the batteries carefully.)

(Switched on)

Why does yours have only one bar?

The other microphones have two bars.

I don't know.

(Clumsy Taehyun)

I want my microphone to be on.

It should record my voice.

(Junho is back with some food.)

Did you buy enough food?

I couldn't get enough food. It's too expensive.

- Did you buy anything? / - Did you buy a lot?

- What did you buy? / - Chicken.

(He bought three chicken skewers.)

Do you have the cameras with you?

(All the cameras are on.)

- Give me some of it. / - Try it.

Have some.

(They decide the next destination sharing food.)

I'll call Seokjin now.

- Who? / - Seokjin.

What time do we need to be there? By five?

(Please.)

- Hello? / - Where are you?

- I'm home. / - What are you doing?

I was vacuuming the house.

I see. We're shooting Two Days and One Night now.

- Okay? / - Our mission is...

(What was it again?)

- The Year of the Dog. / - The Year of the Dog.

Hearing new year's blessing from someone

born in the Year of the Dog.

- Hearing blessing? / - You were born in 1982.

- Yes. / - Can you spare us some time?

Say he's the star representing 1982.

You're chosen as the biggest star

among those born in the Year of the Dog.

We have to meet you.

- You have to meet me? / - Yes, we do.

- What time? / - Now.

(Right now.)

- Now? / - Yes.

(I'm sorry, Seokjin.)

Where are you now anyway?

In front of your house.

- In front of my house? / - Yes.

(He's lying without hesitation.)

Hello.

Can you meet us? Can you make time for it?

- It'll take 20 minutes. / - Okay.

Thank you, Seokjin.

(They go to meet Seokjin who was born in 1982.)

How are we going to take the rest of the pictures?

There should be a tile-roofed house

near the temple. I think we can take it there.

- Siyoon. / - Yes?

You're a good photographer, right?

Take a picture of this as if we took it ourselves.

- I can do that. / - Gosh, really?

Why don't we just save a picture from a website?

- Let's do that. / - What?

- We can just say / - Gosh.

- we took it ourselves. / - And I have my pictures too.

Look.

(Siyoon shows his album.)

- We can use this. / - No one would know.

This photo looks like the one from our mission.

That does look similar.

How long will it take to get there?

Let me check.

It'll take about two and a half hours.

(They'll get there around 5 p.m.)

(They'll have to go into the water at this rate.)

(They've come to meet Seokjin.)

- Should I start filming? / - Yes.

(They're getting ready.)

- Is he here? / - He's here.

- He's here. / - Seokjin.

- Hello. / - There he is.

We're filming it ourselves without the staff.

You're a star born in 1982, the Year of the Dog.

- Yes. / - Nice to meet you.

(Ha Seokjin, the star actor born in 1982)

(He's a handsome actor)

(and a smart guy who majored in engineering.)

It's people born in 1982, 1964, 1994 and so on.

(His good looks stand out.)

- And 1970? / - Yes.

We were looking for people born in 1982 and 1964.

- 1964? Isn't it 1958? / - He meant 1946.

- 1946? I see. / - I meant 1946.

It's our mission to hear

words of blessing from you for the new year.

We need a full shot.

- We should move. / - Let's go.

We need to film a full shot.

Set up the camera here.

(They're somehow trying to get a good shot.)

What are you doing?

(What are you all filming?)

Shouldn't we check his ID card?

Yes, let's check first.

- My ID card? / - Yes.

- You brought it? / - He told me to.

Just show your birthdate.

(It's certain he was born in 1982.)

Let me take a picture of it.

It looks like you're renting an apartment.

- Thank you. / - He was born in February.

Thank you.

We should give our words of blessing to him first.

Seokjin, we hope you'll have a great year.

Happy New Year.

You'll be successful this year.

Two Days and One Night is already a popular show,

and you're all doing so well.

Things are going great for you.

I don't know if you need my words of blessing.

I hope this year will be another good year for you.

I'm happy to see you take good care of Joonyoung.

I hope I'll see Joonyoung often this year too.

What kind of friend is Joonyoung?

(What kind of person is Joonyoung to him?)

A friend I eat lamb skewers with.

We often eat lamb skewers.

That means they're close friends.

Please join our show some time.

Let's go on a trip together.

Well, if we have a chance.

(We'll film you properly then.)

One, two, three.

- Two Days! / - One Night!

(Mission with the star born in 1982 is complete.)

For more infomation >> Ha seokjin!~ words of blessing from you for the new year. [2Days & 1Night-Season 3/2018.02.11] - Duration: 9:39.

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Part 4 A Guide for Laboratory Systems Management: LIMS/LIS, ELN, SDMS, IT & Education - Duration: 44:00.

Hello & Welcome, everyone!

Thank you for joining us for today's webinar, hosted by the LiMSforum.

My name is Dinah Ramirez and I'm your Moderator for today's webinar.

Today's Webinar "A Guide for Laboratory Systems Management is PART 4 of a webinar

series that's been presented by Joe Liscouski!

Today we'll be focusing on LIMS, ELNs, SDMS, IT & Education.

If you're joining us for the first time in the series, Joe is an experienced laboratory

automation/computing professional with over forty years experience in the field, including:

-the design and development of automation systems

- LIMS - robotics and data interchange standards

- and consults on the use of computing in lab work.

We're excited to have Joe with us here again for Part 4 in his series, so let's check-in

with Joe and we'll get started!

Alright, Joe, thanks for joining us!

The floor is yours.

Thanks and welcome to the fourth session in this series.

We'll be continuing to look at the factors in making a choice of central database systems,

the added concerns multi-laboratory environments can bring, and the role that information technology

support groups have in this process.

As we've noted in these webinars, this companion book will provide useful background information

on the technologies, support, and other factors that can impact your ability to effectively

use these systems.

It should prove to be a useful reference as the webinars get into more technical details.

Those details will become more apparent in this session, and I will be making references

to sections of the book for more information.

I'll also provide additional reference material at the end of this webinar.

The previous sessions have introduced the major

systems in laboratory informatics and looked at how the return on investment can be measured

evaluated.

In the last session, webinar 3, we began looking at the points that need to be considered when

choosing between a LIMS, ELN, or SDMS for a single lab, plus the documentation needed

to support those decisions.

At this point we are assuming that you've addressed the issue of what type of central

database system you are going to use as a target: LIMS, ELN, SDMS, or a combination

of them.

At this point we aren't looking at specific products, but rather product characteristics

that fit your workflow: large scale repetitive testing or laboratory work diary.

Our initial focus on the central database system as a starting point is based on a simple

premise: Multiple uncoordinated workflows from isolated workstations will leave you

with multiple sources of data and information that will at some point have to be integrated.

Without that integration, comprehensive lab-wide or even technique-wide data analysis and evaluation

will suffer significantly.

You are better off addressing this need as early as you can in your lab's life.

We looked at these points with regard to a single laboratory…

and now we're going to consider the points that might arise in a multi-laboratory environment,

differing implementation structures, and the role of IT support in this work.

Multiple lab situations can arise for a number of reasons: you may be working at a research

complex, or for a company or organization that has multiple campuses.

One laboratory may do testing in support of research and also develop test methods that

will be put to use in quality control labs.

The questions that we want to address are: - can multiple labs benefit from common product usage

and can they agree on one or more product characteristics that can lead them

to successfully choosing and implementing working systems?

The benefits of focusing on a single product or a small set of products include reduced

purchase costs.

Some informatics systems permit multiple independent datasets to run concurrently; you have the

ability to support several labs with a single license.

If you are buying software for several labs, you have better bargaining power.

The other benefits derive from support costs.

If the number of sites you are working with is large enough, the vendor may offer special

support considerations.

If your IT group is supporting your software, they will have an easier time supporting one

product set, particularly if it involves development work.

In addition, the learning curve for lab personnel will be smoother, and if people transfer between

departments, they will have access to systems that they are already familiar with.

Similarly, meeting the needs of regulatory compliance will be simplified.

All of this works if you don't have to compromise on meeting your laboratories needs.

You don't want to have to sacrifice important features or force-fit LIMS functionality into

an ELN.

However, products that support both workflows would be useful, particularly if needs evolve

one way or the other.

When we are dealing with systems like these, there are additional considerations that have

to be taken into account.

Among them are system backups and archives.

Both are designed to address an important problem: data loss and retrieval.

Everything we've covered so far has been concerned with getting data and information.

It has to be protected from loss as well.

System crash, there are floods, storms, electrical failures, and malware to take into account.

Protection against data loss includes backups and archives.

Backup provides short-term insurance against system failure and data loss.

They are copies, essentially a snapshot, of the entire system or major segments of it

depending on your policies.

Different portions of the system may be backed up at different frequencies.

A backup can be used to restore all or part of a system.

Archives are another form of backup and will include both actively used documents and historical

information organized so that it is easily searched and has the ability to retrieve the

contents, including older versions of documents.

Those have to be backed up as well.

This is a subject that could warrant a session of its own.

I mention it here because of the impact of these activities on IT support and how that

can be affected by the choices made in both product selection and use by multiple labs.

In case you are wondering, I have my work backed up or archived three different ways

including remote archives.

The backup is a current snapshot of the disk drives on the system.

The archives contain historical information including current and older versions of files.

A little paranoia goes a long way.

Why is this important to you?

The shift from paper-based systems to electronic media offers something you didn't have before:

protection against loss of laboratory work, plus the ability to easily re-organize it

and distribute it for use elsewhere.

It also raises a concern that you didn't have before: security against electronic theft

and malicious behavior including ransom-ware and other problems.

We are beginning to define the roles of an outside organization in laboratory work, that

of IT support.

One important characteristic of LIMS and ELNs designed for laboratory work is the ability

to connect instruments and data systems either directly to the database systems or through

an intermediate system like an SDMS.

This is an important selling point for these systems and a key component of improving productivity

and Return On Investment.

Instrument data can be automatically entered into the database and work lists can be sent

from the data-system to instrument/experiment workstations.

How significant these points are, and how they fit into your needs is going be a consideration

in the next few slides.

What we will be covering will have a direct bearing on multi-lab systems support and suitability.

How data and information are collected and moved around the laboratory, between data

sources and destinations, will have some bearing on how you prepare for centralized database

systems and where they are located.

The three primary modes of collection and communications are shown on the screen:

analog data capture with digital controls, serial communications, and Ethernet compliant systems.

These can range from instrument-computer combinations that are one-to-one or many-instruments-to-one-computer,

to devices with built in communications protocols and connectors.

We'll look at the implications for centralized database systems in the next few slides.

The output of an analog device can go to a meter, chart-recorder, or most commonly today,

a computer system.

The instrument (data source) has to be close to the computer to avoid cabling problems

as well as noise elimination.

Normally the computer will provide instrument control (including an autosampler) via digital

switches through a digital I/O card.

The computer provides the analysis of the data, with reporting and communications (usually

via Ethernet or WiFi) to an SDMS system or LIMS/LIS, ELN.

The distance between the instrument computer workstation and the instrument is dependent

on the nature of the control and data signals, acquisition speed, and the options for data

conversion over intermediate networked devices.

High speed data collection and the use of hyphenated techniques argue for close physical

proximity to facilitate acquisition and control.

Low speed devices such as chromatographs would permit longer separations particularly if

care was taken for noise-rejection in cabling.

Since the computer provides data storage and communications buffering, the proximity of

the computer to the centralized data system isn't a problem as long as provision for

fault tolerance to the loss of a network connection is built in.

This becomes more of an issue as the database computer becomes more physically distant from

the instrument system due to the potential for delays and downtime.

The loss of a connection will impact information transfer in both directions; test results

in one direction, work lists in the other.

Some common laboratory devices are really packages of a measuring instrument and computer

control system.

The instrument provides the analog signal and the computer converts it into digital

form and provides serial or Ethernet communications protocols to computer system.

pH meters and balances, are among the devices that fall into this type of instrumentation.

These devices are usually designed to work in two possible modes: front panel controls

operated by a person, and programmable modes that depend on instructions from computers.

Front panel operations are controlled by the analysts needs; take a measurement, transmit

it, etc.

The back-panel command structure is a simple command-and-reply sequence.

For example a balance may be told to record a weight and send it back to a computer.

This requires an active connection, if there is a delay or either the instrument or computer

goes off-line, nothing happens.

LIMS, ELNs, and laboratory execution systems usually have facilities to connect these devices

to a computer and controlling them.

A Laboratory Execution System for example,

may interact with a balance by instructing the analyst to place something on the balance

pan, press a button and then the software records the weight in its data set, ready

to be used in the step of the process.

LIMS and ELNs have similar functions.

If the connection between the software system and device drops out, nothing will happen

and the analyst will have to revert to manual front-panel operations, entering the information

into the database later.

When we talk about connecting instrument to centralized database systems, we aren't

talking about analog or digital interfaces.

What we are looking at is communications between computer systems, exchanging files or serial

data.

Even in those cases, serial communications is best done with the use of a local (to the

lab) intermediate computer.

Connecting instruments, really means connecting the computer systems that are attached to

instruments and transferring files, or if data exchange standards are in place, exchanging

messages.

The problem with serial data is twofold: first there is the lack of an error free communications

protocol with error detection and correction, and, second, considering the previous examples,

there is the possibility of delays in transmission resulting in problems carrying out lab tasks.

It is easier to let a local computer handle the instrument responses and package the resulting

information in a file transmitted over networks.

Fundamentally, time critical, fast response tasks should be serviced by local-to-the-lab

computers.

This is part of the planning needed in laying out lab networks.

When files are transmitted by an instrument workstation to a LIMS, ELN, LES or SDMS, they

are received and analyzed to extract the necessary information.

The information is then entered into the database system.

The words "interfacing" and "communications" are not synonyms.

They represent different technologies, and we have to be careful how they are applied

to laboratory work.

It's important to understand the distinction between the "instrument" and the "data

system".

We don't normally interface instruments to LIMS/ELNs.

The interfacing is done through a computer system that communicates to the LIMS/ELNs.

We'll go into instrument interfacing and data systems in more detail in a later session,

it is very important to the design of your labs technology.

The need for a distinction between "interfacing" and "communications" will begin to become

clear in the next few slides.

This is a simple situation: one lab, one system.

With this arrangement the lab has complete flexibility in connecting instrumentation

to the LIMS or ELN, as well as configuring the database to meet their needs.

If specialized programming is needed to support an instrument, the lab has the freedom to

do so.

All of the instrument types in the previous slides could be supported.

One consideration in particular is worth noting: commercial data systems have a library of

software available to support instrumentation and make instrument-computer connections easier.

What happens if your device isn't supported.

If it is a low cost device, it might be far easier and less costly to replace with one

that is.

If not, find something similar and modify the software.

Otherwise you have an add-on project.

Instrument support requirements should be part of the user requirements.

Software modifications are an IT issue.

Until the advent of high-speed networks, this was the typical laboratory system configuration.

IT would be responsible for hardware support, operating systems, and infrastructure, as

well as system backup.

The support for the lab application software might come from corporate IT, but might also

be a lab function or contracted to a 3rd party.

The multiple lab variation is just a repeat configuration for each lab.

With this arrangement the labs retain complete flexibility in connecting instrumentation

to the LIMS or ELN, as well as configuring the database to meet their needs.

If specialized programming is needed to support an instrument, the lab has the freedom to

do so.

If different labs have similar interconnection needs, the development work done for one lab

can be repeated elsewhere.

This is one clear benefit for standardizing on product sets as long as it doesn't compromise

the labs work.

This situation could be replicated for a number of labs based on the same products, each lab

having full independence.

IT support would have to manage multiple computer systems dealing with support, updates, and

so on.

Each system would be individually backed up and the data system archived, as noted earlier

this could be done automatically.

This puts a considerable burden on IT staff, which could be mitigated by automated backup

procedures.

Backup and archiving facilities would have to be incorporated into the user requirements

along with the policies for backup frequency and archiving of backups.

There would also have to be periodic testing of the backups and archives to make sure the

process is working.

The next variation provides support benefits, but starts putting some complexity into the

system.

In this arrangement we have 3 independent labs sharing access to a common LIMS installation

(could be an ELN, or a multi-functional system) with each lab having its own copy of a database;

note: not all vendors support this configuration.

This could be considered as a variation of the software-as-a-service model, with the

software hosted on a private corporate server instead of the vendors.

Another variation is the use of virtualization.

Virtualization is a software technology that allows one or more servers to host multiple

copies of software running independently.

There are some benefits and limitations that are imposed on the lab.

Note: the SDMS is configured to be local-to-the-lab in order to facilitate tasks that need fast

responses.

There are multiple configurations possible with these systems and you have evaluate your

needs to determine the one most appropriate for your work.

From the labs standpoint they have access to fully functional centralized database systems:

LIMS or ELNs for example.

Laboratory data is concentrated in the SDMS with necessary information passed through

to the central database system.

The SDMS acts a buffer or primary storage for laboratory instrument data.

The centralized data system would not be modified to meet individual labs needs.

This is necessary to ensure that the data systems are easily upgraded and supported

without having to re-implement custom modifications.

Those modifications would be implemented in the SDMS which is supported by each laboratory's

independent configuration.

The major benefits are in the cost of the system when compared to purchasing and installing

multiple independent systems, the cost reduction for support and maintenance,

making it easier to add

additional labs, and the ease of providing backup and archiving.

Security and physical access control is provided by IT staff.

One popular technology application is moving software and data systems to the cloud.

From a network topology standpoint, this configuration and that on the previous slide are pretty

much the same.

The list of benefits from cloud implementations, particularly those that are vendor supported,

are considerable.

However the issues do need attention.

One of the obvious points is that the server for the database system isn't anywhere you are

likely to be able to visit.

And that raises some issue of it own.

We are used having the web take us virtually anywhere in the world with a few clicks, and

having the results pop up quickly.

We can enter information into systems without having any idea where they are, and expect

good response times.

Networks are fast enough that we are able to distinguish between the response times

for areas with well developed networks and those with less sophisticated systems.

Right now we are experiencing an example of the networks capabilities; I'm in Massachusetts,

our producer is in Michigan, and you are all over the place.

The distance between client and server systems can be measured in two ways: the time it takes

to send/receive data/information, and, the physical separation between them.

In most cases the physical separation doesn't matter, but the point-to-point physical span

can have significant impact on performance when life is less than ideal.

When we are in a planning process we have to work against potential problems, including

the security of your intellectual property.

When the servers move off-campus distance concerns increase, and new ones are added:

Those are security, downtime, delays, and legal issues.

Geographically distributed networks raise some issues.

The most obvious are delays and interruptions, those 404, file not found errors.

Or the "email delayed" messages.

They aren't frequent, but they happen.

Planning for them is essential.

Even situations like the one we are experiencing now can have problems that need to be planned

for, and I hope I didn't just jinks it.

For example we have rehearsal recordings that we can use if something prevents a live presentation.

The problem for your lab is: "what happens if your connection to your LIMS or ELN is

lost?"

What are the vendors backup plans?

Do they have redundant systems that you can switch to if there is a problem?

How often are they synchronized?

Do you know how to access them?

Have you tested the process?

The further away you are from the server the more room they have for problems to occur.

Among the causes for problems are power outages, storms like the large hurricanes experienced

in the US and elsewhere, and the potential for earthquakes.

You may feel that you are in a safe area, but how about your vendor's servers and

the space in between?

These aren't reasons to avoid using the technologies available, but areas where planning

has to be done, including testing, running the equivalent of fire drills to make sure

that plans actually work.

This is a subject where your IT groups experience, in conjunction with your vendors come into

play.

The time to make these plans is before implementation has begun, in fact, before you sign anything.

Another concern is security.

The networks we rely upon are global in extent.

So are the people who would like to have access to your data and information.

Are your corporate and remote systems protected against attacks that can include unauthorized

access, malware, denial of services, ransom ware, and other unpleasant issues.

The typical SAAS vendor will say that their security is better than your corporate systems.

This is another area where your IT group can work with your prospective vendors to ensure

functioning and safe systems.

The last point I want to make on this subject is legal issues.

When you are using software hosted on 3rd party platforms you become subject to a number

of legal issues that may originate in your location, country, or the country where your

servers are located.

For example, you may be working with a Software-as-a-Service vendor

for a database, and they host it on

a sub-contractors server farm that has locations in your country or another.

Each of these can contribute to legal concerns.

And you may not have done anything wrong.

Vendors may offer the option of hosting your database and software on either a private

server or a shared system.

If you are on a shared system, and someone else does something bad, the entire server

may be impounded, including your data.

The laws on this subject vary widely by country, and it is an evolving issue.

This is one where both IT and your legal department may need to be included before finalizing

the relationship with the vendor.

We began this presentation looking at the options for lab informatics, with all systems

residing within the labs walls, and then considered the possibility of reducing costs by several

labs using the same products. That depends upon individual labs needs analysis

converging down to compatible solutions.

That being the case, we then looked at the ramifications of consolidating systems into

shared on-site servers and then having those databases hosted by off-site 3rd party vendors,

the Software-as-a-Service model.

We also looked at how instrument interfacing, data systems, and communication affected the

distribution of informatics inside the lab and working with remote systems.

In the previous webinar, we made a statement that even startup labs need to focus on the

centralized database as one of their initial priorities, determining if they need a LIMS

or ELN for example to support their labs information capture and analysis.

Vendor supported Software-as-a-Service models may be a good way to implement those tools

while minimizing the financial investment.

In all of this, we made frequent reference to the role of IT support.

Now it is time to begin looking at that subject in more detail.

We first raised the Information Technology Support issue in webinar 3, when we discussed

needs development.

Now as we start looking at implementation and support options, particularly when the

central database system might migrate from the lab to on-campus hosting and then to off-site,

possibly by 3rd party support, the need for coordination with IT becomes more important.

There are shared responsibilities between lab personnel and IT support for the successful

use of informatics systems in the lab.

As we've discussed the lab user community is responsible for determining what is needed

and how it should function.

They have to be intimately involved in product specification and selection, as well as evaluating

the implementation options and the final system.

This stuff directly impacts their ability to work, and, the validity of the lab processes

being executed.

So what exactly should the role of IT be?

They aren't just people who support hardware and software, they need to be advisors on

software issues and in particular support.

That includes their ability to support users, and, their evaluation of vendor's ability

to support products and ensure that they are working properly.

This world is a lot more complex than office products, and people need to have the right

balance of skills to be successful, your laboratory depends on it.

We need to consider the role of corporate IT, and the possible addition of a LAB-IT

function.

In most organizations, corporate IT is responsible for hardware support, operating systems, and

frequently used applications software, office applications for example as well as corporate

database systems, and in many companies enterprise resource planning systems, and help desk support.

Enterprise resource planning includes a number of functions that run the businesses including

customer service, human resources, accounting, production, sales, and so on.

These are large, expensive system that can encompass an entire business operation.

We'll get to how that can impact your lab later, probably in the next webinar.

While the capabilities provided by corporate IT are important to the labs operation, fully

supporting laboratories is usually a bit outside their experience.

The items on the left are what companies typically see as a description of IT support.

Organizations that support manufacturing and scientific work may be able to justify personnel

that are specialized in those fields.

In some cases you may have people holding advanced scientific or engineering degrees

providing an IT support function.

The items on the right are more typical of laboratory systems.

The first bullet for example might be at odds with corporate policies of upgrading operating

systems; in a lab an upgrade could be a disaster.

There are a large number of lab applications found in any facility, which is a significant

contrast to most business operations.

Vendors can skimp on documentation, they are more interested in the technical aspect of

their products than effective user documentation and support.

The impact of system problems can be serious.

Problems can easily snowball as work gets backed up.

And finally it is really hard to find people with the skills needed to support lab work.

It isn't just technical know-how, it's people skills, trouble-shooting, and problems

solving.

With a wee bit of pressure added to keep it interesting.

What we need to do is to develop professionals with a balance of skills to meet the increasingly

complex demands of technology management in scientific and laboratory work.

At one time that might have meant understanding LIMS or ELNs, or robotics, or instrument interfacing.

Now it is a complex and specialized mix of talents needed to bridge science and technology.

The work may expand to include modeling, simulation, and the ability to handle Big-Data computing

applications and analysis.

Beyond that, these people will need to be able to understand the needs of scientists

and develop the tools to meet their labs needs.

This is where session five will begin.

And that is currently scheduled for April 26th.

During this session we've covered a lot of ground including the ability for multiple

labs to use common products, and the options for various levels of managing central databases

on the corporate and cloud levels.

Vendor hosted cloud systems could provide an easy entry point for small lab into informatics

technologies.

Care should be taken to ensure that they meet your requirements, and that they provide a

migration path to corporate on-premise hosting should that be desirable.

There will be a slide following this one in the handouts (PDF) you will have access to as part of

the webinar series.

It will have a list of additional references that will be useful for the labs work.

That's the end of the formal presentation.

Are there any questions that people would like to address?

Thank you Joe!

I'd like to remind everyone that you can submit your

questions or comments using the chat box on the right-hand side of your screen.

So feel free to go ahead and do that.

While we wait for any questions or comments to come through, we do have a few questions

for Joe that came in that he'd like to address.

So, we'll go ahead and address those questions

and we'll give you a few moments if you do want to go ahead and submit any of your questions or comments.

I also want to mention that we will be providing a recording and the

slides to everyone after the webinar today.

It will be posted on the LiMSforum.

I know we did get a few of those questions and comments in the chatbox earlier.

Ok, so Joe here's one of the first few questions here.

You mentioned that the first major component of lab informatics should be the central database system.

How do you protect yourself from making a mistake?

Well, the major approach to doing that is making sure you've done a thorough job of specifying the system.

Really figure out what it is you need to get done, what you want the system to accomplish

and what model, whether it be the LIMS model or ELN model, fits what your workflow is.

You need to talk to people who are knowledgeable in the field

and look for systems that provide for flexibility.

There are a number of them and the number is increasing

that support both LIMS and ELN functions,

so it might be easier to transition between the two of them.

But the real one, the real kicker,

is making sure you do a really good analysis and evaluation of what it is you need to get accomplished

and how your lab wants to work.

Ok great! And here is another question that we received.

What if IT support people are pushing for a system based on their ERP system? Is this a good idea?

Usually not, we'll be going into some more detail in webinar 5.

We look at more about the details of IT support and start looking at some build or buy solutions.

IT people that are using enterprise resource planning systems

have invested a lot of effort, a lot of time, and a lot of money, and a lot of training

to learn how to use those systems.

And they may have sold them on the idea that these systems are gonna do everything

that the company needs to have done.

And then the lab people raise their hand...

and there's a lot of things in labs that they probably haven't considered.

They may try to build the system around an ERP

but that's usually not a good idea...some people have done it...

but the builder or buy solution, the build or buy problem is a significant one.

It really needs a lot of thought and a lot of work.

Okay, interesting, great!

There's one last question that we received in advance here

and we'll see if any additional questions come through the chat box.

How realistic is it to want to connect instruments to a remote database system from the lab?

All right, you remember there is a distinction between the instrument which provides an analog output

and the computer system.

And in many cases when a salesman sells you an instrument,

they automatically sell you the computer as if they're the same thing.

You don't connect instruments the analog output to remote computers...it simply doesn't work.

What you really do is communicate the database structure.

File sharing, for example, between the computer that's attached to the instrument to a remote computer.

So often, when you talk to a Salesman, you'll say I want to reconnect this instrument to

my LIMS system or a remote ELN.

What you're really doing is a computer to computer connection, not the instrument itself

as part of the instrument package.

Okay great, thank you for answering those questions.

It does look like we have a couple questions that came in through the chat window as well.

This first one here... it looks like, it seems like the question is asking:

Can you provide criteria to consider for remote server hosting?

What do you mean by criteria?

Basically, when you're dealing with a remote server you're really dealing with

something akin to a time sharing...

...a time sharing operation

where you're sending data to an instrument, you're sending data to a remote database

and getting information back.

It's a lot like working with a web browser.

So among the things you want to be concerned about are response times, response speed,

how the data is being controlled, uptime on the servers, that kind of thing.

Basically ensure that when the server is there, when you need the server to be there, it'll be there working.

Not quite sure what it is you're trying to get at.

Okay yeah, if there's some more clarification that's needed,

just let us know in the chat box, but hopefully that answered your question regarding hosting.

Yep, if it didn't on the bottom of the slides is my email address. Just send me a note and we can talk that way.

Okay great, that's wonderful that you've provided your contact information Joe so that if anyone wants to

speak with you one-on-one then you can certainly contact Joe and he's a great resource for that.

And it does look like that does answer Nathan's question there.

Another question that came through is:

What is the difference between a traditional SDMS and a LIMS that has a module that emulates similar

functionality, but is not considered a true SDMS?

An example is provided...

Ex. A lab where it doesn't have an SDMS, but says they have similar functionality through a module.

Well, it's a lot like saying you've got something that looks just like a duck but it's not quite a duck.

It's kind of hard to answer that question without knowing what your situation is.

SDMS's have been around for a while.

Waters has a number of them.

A matter of fact, Waters was originally provided by a third party and became part of their system.

The question really comes down to is, what do you need to have done?

An SDMS can be looked at as being a very large filing cabinet that can handle a lot of different stuff:

Reports, documents, images, instrument data... that's sorted by project, by instrument type, sample types...

you can sort things a number of different ways.

So the easiest way to answer that question, is say:

These are the functions I need. These are the facilities that I need. This is how I want my lab to work.

Does the SDMS meet those needs?

And then, when you turn around to a LIMS vendor, for example, and look at what they provide...

...you can say fine, does your system meet all these needs? Or is there a lot of hacking or a lot of software

development that has to be done to get things working?

An SDMS provides a point of connection for a lot of instrumentation,

a place where a lot of data can get dumped that doesn't fit into a LIMS file structure.

And then the parts that do belong in the LIMS file structure can be extracted and moved forward.

So again, a lot depends on what problem you want to solve.

Okay, great. Thanks for answering that and of course if you do want to talk with Joe, one-on-one, his email

is available on the slides and we've provided it through our communication emails,

so you can dig there as well.

It does look like that did address their question Joe, so thank you.

Joe's email address again is joe.liscouski@gmail.com

It will be in the slides, so you can connect with him.

I don't see any other questions that are coming through at this point in time.

What we can do is we can start with our closing information and of course if any other questions

come through, feel free to go ahead and submit those. But it looks like we've covered all of those questions.

Joe is there anything else that you would want to cover before we go ahead and wrap up here today?

Just thank you for you being here and as I said the next session we're going to get into more

information about IT support; that tends to be a very important question.

We'll be beginning to look at the build or buy; and then future sessions will look at instrumentation,

instrument data systems, and moving down the line to sample preparation.

Okay great, thank you so much Joe! It doesn't look like there's anything else coming through,

so I believe that that will conclude our webinar session here today! Thank you so much!

And as a reminder we will be sending a follow-up to everyone registered with a link to the recording,

as well as the slides. You can locate Parts 1, 2, & 3 of this webinar series on the LiMSforum

and we'll include that in our follow-up email as well.

So we'll see you next time and thank you so much!

For more infomation >> Part 4 A Guide for Laboratory Systems Management: LIMS/LIS, ELN, SDMS, IT & Education - Duration: 44:00.

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Deputy Micah Flick's widow thanks community, calls for change in future - Duration: 2:50.

For more infomation >> Deputy Micah Flick's widow thanks community, calls for change in future - Duration: 2:50.

-------------------------------------------

'Grey's Anatomy' Returns: Top Spoilers for Tonight | Heavy.com | SML TV - Duration: 5:14.

'Grey's Anatomy' Returns: Top Spoilers for Tonight | Heavy.com

After taking a hiatus for the Winter Olympics, Grey's Anatomy is finally back with an all-new episode.

Tonight, episode 13 of the 14th season will air at 8pm ET/PT on ABC, and is titled, "You Really Got a Hold On Me.".

The official synopsis reads, "Seattle firefighters Ben Warren and Andy Herrera head to Grey Sloan after rescuing two boys who were injured in a house fire; the doctors work on their projects for the surgical innovation contest; Amelia brings Tom Koracick in to consult.

ABC"You Really Got a Hold on Me" – Seattle firefighters Ben Warren and Andy Herrera head to Grey Sloan after rescuing two boys that are injured in a house fire.

With one of the boys' lives literally in Andy's hands, her skills are put to the test.

New Faces.

We'll be meeting plenty of new faces on tonight's episode, as it's serving as the backdoor pilot for the new firefighter spinoff, Station 19.

Andy Herrera, who fans will meet tonight, is played by actress Jaina Lee Ortiz.

Ortiz will play the starring role in Station 19, which will premiere on March 22.

In a recent interview with Variety, Ortiz said, "Just to be part of TGIT is super exciting in itself.

I can't even believe in it… That I got to work with Ellen Pompeo was like an actor's lottery ticket.

I felt super proud and grateful and honored.".

Ortiz said that as soon as Shonda Rhimes' name was mentioned, she was hooked.

"It's just good storytelling surrounded by strong characters and high-stakes.

It's fast-paced.

Shonda's shows are the types of shows that you can't watch while you're doing laundry or you're cooking…You have to pay attention because if not, you miss it.".

April.

There haven't been many spoilers released about tonight, but one thing we know for sure is that April has had an extremely tough time this season on the show, and that's only going to get worse.

Throughout the past few episodes, she's faced obstacles like watching her ex-fiance's wife die in labor.

April has also been sleeping with an intern and is drinking a lot, and there's no saying how she's going to progress as time goes on.

EW's "Spoiler Room" recently revealed, "April's newfound carefree personality won't go unnoticed by Jackson, leading to a confrontation between them that won't go the way that Jackson expects — and probably won't make Japril fans happy.

But is April ready to move on from Jackson? The actress, herself, admitted that she's not.

The two have finalized their divorce and April has told Maggie about Jackson's feelings for her– all this has put April in worse shape.

Speaking to TV Guide, actress Sarah Drew said, "I think she'd like to say that she's moving on.

I think she knows that's the most evolved thing to do but I don't think she's there yet.".

The Surgical Innovation Contest.

In the last episode, which aired February 8, the surgical contest announced its finalists.

It was heartbreaking to see that Alex, Amelia, Deluca, and Sam hadn't made it to the next round in the career-defining competition.

Those chosen will be continuing their research on this episode.

For more infomation >> 'Grey's Anatomy' Returns: Top Spoilers for Tonight | Heavy.com | SML TV - Duration: 5:14.

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Q2 Weather: with Bob McGuire for March 1, 2018 - Duration: 6:08.

For more infomation >> Q2 Weather: with Bob McGuire for March 1, 2018 - Duration: 6:08.

-------------------------------------------

Watch: Oh My Girl's Hyojung Releases Sweet MV For "Mystery Queen 2" OST "SARR" - Duration: 2:18.

Watch: Oh My Girl's Hyojung Releases Sweet MV For "Mystery Queen 2" OST "SARR"

Oh My Girls Hyojung has released a music video for SARR, her OST for Mystery Queen 2!.

The song is a acoustic medium-tempo track that highlights Hyojungs sweet vocal tone as she sings of love like spring warmth that melts the winter cold away.

The acoustic sound and simple chord progressions keep the song light and bubbly.

Soompi. Display. News. English.

300x250. BTF Soompi. Mobile. English.

300x250. ATF.

The music video perfectly matches the song as it begins with a man and a woman sitting on opposite ends of a bench and catching glimpses of each other.

By the end of the clip, they are sitting side by side, staring into each others eyes.

Check out the song below!.

Mystery Queen 2 is the second season of the popular KBS 2TV drama and follows Choi Kang Hee and Kwon Sang Woo as they team up to solve the mysteries behind difficult cases.

The drama aired its first episode on February 28, check it out below!.

Source ().

For more infomation >> Watch: Oh My Girl's Hyojung Releases Sweet MV For "Mystery Queen 2" OST "SARR" - Duration: 2:18.

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Truck Driver Facing Charges For Causing Fatal Crash While On His Smartphone - Duration: 2:41.

TO MAKE THAT DETERMINATION ON

THE CAUSE OF DEATH.

>> DENNIS: A WISCONSIN TRUCK

DRIVER ACCUSED OF USING HIS

SMARTPHONE BEFORE CAUSING A

FATAL ACCIDENT NEAR ST. PAUL IS

FACING CRIMINAL CHARGES.

WASHINGTON COUNTY PROSECUTORS

SAY 28-YEAR-OLD WAYNE HICKS OF

INDEPENDENCE, WISCONSIN, IS

CHARGED WITH CRIMINAL VEHICULAR

HOMICIDE IN TIEWS OF TUESDAY

AFTERNOON'S CRASH THAT KILLED

54-YEAR-OLD ROBERT BURSICK OF

AMERY, WISCONSIN.

PROSECUTORS SAY HICKS ADMITTED

TO TEXTING WITH HIS GIRLFRIEND

AND SEARCHING AN APP FOR HOUSES

ON HIS PHONE PRIOR TO THE CRAIK

IN LAKE ELMO.

THE COMPLAINT SAYS HICKS WAS

GOING 63 MILES PER HOUR AND MADE

NO EFFORT TO STOP BEFORE REAR

ENDING BURSICK'S VIDEO.

>> I HAVE WATCHED THE VIDEO

MYSELF SEVERAL TIMES, AND AS THE

COLONEL SAID, IT'S ABSOLUTELY

HORRIFIC.

IT'S DESCRIBED IN DETAIL.

THERE WERE CAMERAS OR SPLIT

SCREEN LOOKING FORWARD THROUGH

THE WINDSHIELD AND ALSO LOOKING

INTO THE CAB OF THE VEHICLE, AND

ACCORDING -- AS I PUT IN THE

COMPLAINT, THE DRIVER IS SEEN

AND APPEARS TO BE LOOKING AT HIS

PHONE FOR AT LEAST AN ENTIRE 8

SECONDS BEFORE STRIKING THE

VEHICLE.

HE DOESN'T APPEAR TO LOOK UP

INTO THE WINDSHIELD UNTIL THE

POINT OF IMPACT OR AFTER THE

POINT OF IMPACT, ONCE HE'S

REALIZED HE'S HIT SOMEBODY.

THE VEHICLE WAS SO DAMAGE.

ONE, IT WAS UNRECOGNIZABLE.

THE BACK END WAS PUSHED UP SO

FAR ALL THE WAY INTO THE

DRIVER'S SEAT.

THE SIDES OF THE VEHICLE WERE

COMPLETELY MANGLED.

THEY WERE UNABLE TO EXTRACT HIM

AT THE SCENE.

SO THE VEHICLE WAS TOWED TO A

LOCAL FIRE DEPARTMENT.

MY UNDERSTANDING IS THEY SPENT

HOURS TAKING THE CAR APART IN

ORDER TO TAKE HIS BODY OUT.

>> WHAT WE NEED TO DO IS GET TO

THE POINT WHERE WE ALL SAY

ENOUGH IS ENOUGH AND WE COMMIT

TO PUTTING EVERYTHING ELSE DOWN

AND PUTTING EVERYTHING ELSE AWAY

AND GIVING OUR FULL ATTENTION TO

DRIVING.

HAD THAT HAPPENED ON TUESDAY

AFTERNOON, THERE'S NO DOUBT IN

MY MIND THAT MR. BURSICK WOULD

HAVE BEEN HOME TO HIS FAMILY

INSTEAD OF HEADED TO THE MORGUE.

>> WE DO HAVE AN EPIDEMIC, AS

THE COLONEL SAYS, ON OUR ROADS.

ONE IN FOUR MOTOR VEHICLE

CRASHES IS DIRECTLY OO ATTRIBUTD

TO A DISTRACTED DRIVER.

AN AVERAGE OF 65 LIVES A YEAR

ARE LOST IN MINNESOTA BECAUSE OF

A DISTRACTED DRIVER.

THIS CRASH IS JUST THE LATEST IN

THAT LITANY OF TRAGEDIES THAT

LITTERS OUR ROADWAYS AND DITCHES

AROUND THEM.

>> DENNIS: HICKS COULD BE

For more infomation >> Truck Driver Facing Charges For Causing Fatal Crash While On His Smartphone - Duration: 2:41.

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Learn Animals Name and Sound for Kids - Duration: 5:34.

Learn Animals Name and Sound for Kids

For more infomation >> Learn Animals Name and Sound for Kids - Duration: 5:34.

-------------------------------------------

iKON Announces Plans For Second Dome Tour In Japan - Duration: 2:11.

iKON Announces Plans For Second Dome Tour In Japan

iKON will be embarking on a dome tour in Japan for the second consecutive year!.

On March 1, YG Entertainment announced that iKON would be kicking off its second Japanese dome tour later this year.

The tour will consist of 10 concerts in four cities and will take place during the second half of 2018.

Soompi. Display. News. English.

300x250. BTF Soompi. Mobile. English.

300x250. ATF.

According to the agency, iKON is scheduled to perform in Fukuoka on August 25 and 26, Nagoya on September 4 and 5, Tokyo on November 6 and 7, and Osaka on December 22 and 23.

iKONs latest title track, , is currently enjoying an impressive winning streak on the Korean music charts: it recently became the idol group song with the at No.

1 since 2008.

The group will also be releasing a on March 5.

Source ().

For more infomation >> iKON Announces Plans For Second Dome Tour In Japan - Duration: 2:11.

-------------------------------------------

Woodland Park Schools reopen for Friday followng threat - Duration: 0:21.

For more infomation >> Woodland Park Schools reopen for Friday followng threat - Duration: 0:21.

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State Rep. Metsa Running For Rick Nolan's Seat - Duration: 0:55.

>> DENNIS: HICKS COULD BE

SENTENCED TO UP TO 10 YEARS IN

PRISON IF CONVICTED.

>> DENNIS: DEMOCRATIC STATE

REPRESENTATIVE JASON METSA IS

ENTERING THE RACE TO REPLACE

REPRESENTATIVE RICK NOLAN IN

CONGRESS.

METSA ANNOUNCED HIS CAMPAIGN

THURSDAY FOR NORTHEASTERN

MINNESOTA'S MASSIVE 8th

CONGRESSIONAL DISTRICT.

THE THIRD TERM LAWMAKER IS JUST

THE LATEST DEMOCRAT TO ENTER THE

RACE SINCE NOLAN ANNOUNCED LAST

MONTH HE WON'T SEEK REELECTION.

FORMER F.B.I. COUNTER-TERRORISM

ANALYST LEAH PHIFER WAS ALREADY

IN THE RACE BEFORE NOLAN DROPPED

OUT.

FORMER STATE REPRESENTATIVE JOE

RADINOVICH, NORTH BRANCH MAYOR

SCIR STEN HAGEN KENNEDY AND LONG

TIME DULUTH NEWS ANCHOR MICHELLE

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